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2022”Ni6ŒŽŒťÝj
Œ´’˜˜_•ś
Sakiyama, Y., Nagata, M., Yoshida, R. (equal contributors), Kasho, K., Ozaki, S., and Katayama. T. (2022)
Concerted actions of DnaA complexes with DNA unwinding sequences within and flanking replication origin oriC promote DnaB helicase loading
J. Biol. Chem. 298(6): 102051
ƒI[ƒvƒ“ƒAƒNƒZƒX doi: 10.1016/j.jbc.2022.102051
Žĺ—vŠw‰ď”­•\
Tsutomu Katayama
Dynamic mechanisms constituting regulation for the replication initiator DnaA protein in Escherichia coli
Major ideas in quantitative microbial physiology: Past, Present and Future
(June 13-15, 2022, The Carlsberg Academy, Copenhagen, Denmark) ľ‘ҍu‰‰

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‘ć18‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ďi‚UŒŽ27-28“ú@•xŽRŽsjŒű“Ş•”–ĺŒ¤‹†ÜŽóÜ

2021”N
Œ´’˜˜_•ś
Ozaki, S., Wakasugi, Y. (co-first authors), and Katayama, T. (2021)
Z-ring-associated proteins regulate clustering of the replication terminus-binding protein ZapT in Caulobacter crescentus
mBio. 12 (1): issue e02196-20 ƒI[ƒvƒ“ƒAƒNƒZƒX

Kasho, K., Oshima, T., Chumsakul, O., Nakamura, K., Fukamachi, K., and Katayama, T. (2021)
Whole-genome analysis reveals that the nucleoid protein IHF predominantly binds to the replication origin oriC specifically at the time of initiation
Front. Microbiol. 12: 697712@(16 pages)@@
ƒI[ƒvƒ“ƒAƒNƒZƒX doi: 10.3389/fmicb.2021.697712

Miyoshi, K., Tatsumoto, Y., Ozaki, S., and Katayama, T. (2021)
Negative feedback for DARS2-Fis complex by ATP-DnaA supports the cell cycle-coordinated regulation for chromosome replication
Nucleic Acids Res. 49(22): 12820-12835
ƒI[ƒvƒ“ƒAƒNƒZƒX doi: org/10.1093/nar/gkab1171
Faculty Options (‹Œ F1000Prime) „‘E˜_•ś‚É‘I‚΂ę‚Ü‚ľ‚˝i2022.1j

Žĺ—vŠw‰ď”­•\
Tsutomu Katayama
Regulatory systems underlying the replication cycle of the chromosome in eubacteria
The 6th JAPAN-TAIWAN Joint Symposium For Pharmaceutical Sciences (August 27 held Online by Kyushu University)

Tsutomu Katayama, Kenya Miyoshi, Ryusei Yoshida, Chuyuan Lu, Lanyang Li, Kazuma Korogi, Yuka Tatsumoto, Kosuke Ito, Hironori Kawakami, Kazutoshi Kasho, Shogo Ozaki
Dynamic nucleoprotein complexes and DNA structural changes supporting regulated replication initiation of the Escherichia coli chromosome
‘ć44‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒVƒ“ƒ|ƒWƒEƒ€uThe common mechanism for regulation of genome maintenance by DNA structural dynamicsv Organizers: Kazutoshi Kasho, Tsutomu Katayamai12ŒŽ‚P`‚R“ú@ƒpƒVƒtƒBƒR‰Ą•lj

Shogo Ozaki, Tsutomu Katayama
Analysis of the chromosomal replication mechanism in the eubacterium Caulobacter crescentus
‘ć44‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒ[ƒNƒVƒ‡ƒbƒvuWhat is life in a microbe?v Organizers: Shogo Ozaki, Setsu Katoi12ŒŽ‚P`‚R“ú@ƒpƒVƒtƒBƒR‰Ą•lj

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Žá™‘׌hA”öčČŒáA•ĐŽR •×
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‘ć94‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď ƒVƒ“ƒ|ƒWƒEƒ€uőF‘Ě‚Ě‘˝—l‚Č‹@”\‚đŽx‚Ś‚éƒ^ƒ“ƒpƒNŽż‚ŽŸ•Ą‡‘́vi11ŒŽ3-5“ú ƒIƒ“ƒ‰ƒCƒ“ŠJĂj

‰Áś˜aŽőA‘哇@‘ńAOnuma ChumsakulA’†‘şŒ’‰îA[’Ź˜a‹MA•ĐŽR@•×
‘ĺ’°‹Ű‚ĚŠj—l‘Ě’`”’ŽżIHF‚̓Qƒmƒ€•ĄťŠJŽnŽžŠú‚É‚¨‚˘‚Ä•ĄťŠJŽn“_oriC‚Ć“ÁˆŮ“I‚ÉŒ‹‡‚ˇ‚é
‘ć94‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ďi11ŒŽ3-5“ú ƒIƒ“ƒ‰ƒCƒ“ŠJĂj

2020”N
Œ´’˜˜_•ś
Nagata, K., Okada, A., Ohtsuka, J., Ohkuri, T., Akama, Y., Sakiyama, Y., Miyazaki, E., Horita, S., Katayama, T., Ueda, T., and Tanokura, M. (2020)
Crystal structure of the complex of the interaction domains of E. coli DnaB helicase and DnaC helicase loader: Structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding.
J. Biochem. 167(1): 1-14
https://doi.org/10.1093/jb/mvz087
(in Rapid Communication; Published online, Oct. 30, 2019)
“ú–{ś‰ťŠw‰ďJB˜_•śÜ‚đŽóÜ‚ľ‚Ü‚ľ‚˝i2021.7j

Ozaki, S., Jenal, U., and Katayama, T. (2020)
Novel divisome-associated protein spatially coupling the Z-ring with the chromosomal replication terminus in Caulobacter crescentus.
mBio. 11(2): issue e00487-20. doi: 10.1128/mBio.00487-20.

Hayashi, C., Miyazaki, E. (equal contributors), Ozaki, S., Abe, Y., and Katayama, T. (2020)
DnaB helicase is recruited to the replication initiation complex via binding of DnaA domain I to the lateral surface of the DnaB N-terminal domain
J. Biol. Chem. 295(32):11131-11143.@@doi/10.1074/jbc.RA120.014235

Žĺ—vŠw‰ď”­•\
Tsutomu Katayama, Kenya Miyoshi, Ryusei Yoshida, Chuyuan Lu, Kazuma Korogi, Kosuke Ito, Kazutoshi Kasho, Hironori Kawakami, Mariko Nagata and Shogo Ozaki
Molecular mechanisms of specific nucleoid proteins in regulations for the replication initiation of the Escherichia coli chromosome
‘ć43‰ń “ú–{•ŞŽqś•¨Šw‰ď”N‰ď Workshop gFrontiers of nucleoid DNA replication and quality controlh(Organizers; Kazutoshi Kasho and Tsutomu Katayama) (‚P‚QŒŽ‚Q“úi…j`‚S“úi‹ŕ)FƒIƒ“ƒ‰ƒCƒ“ŠJĂ:)

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‘ć14‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ď”N‰ď (ƒEƒCƒ“ƒN‚ ‚˘‚ż 3ŒŽ6“ú`8“ú: VŒ^ƒRƒƒiƒEƒCƒ‹ƒX‘Ήž‚Ě‚˝‚ߎăŠJĂ)

‹g“c—łŻA”öčČŒáA•ĐŽR@•×
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‘ć14‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ď”N‰ď (ƒEƒCƒ“ƒN‚ ‚˘‚ż 3ŒŽ6“ú`8“ú: VŒ^ƒRƒƒiƒEƒCƒ‹ƒX‘Ήž‚Ě‚˝‚ߎăŠJĂ)

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‘ć14‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ď”N‰ď (ƒEƒCƒ“ƒN‚ ‚˘‚ż 3ŒŽ6“ú`8“ú: VŒ^ƒRƒƒiƒEƒCƒ‹ƒX‘Ήž‚Ě‚˝‚ߎăŠJĂ)

Ḡ‘^ŒłA”öčČŒáA•ĐŽR •×
‚“xD”MŤ^ł×‹ŰThermotoga maritima‚Ě•Ąť‹N“_oriC‚É‚¨‚˘‚ÄDnaA‚Ć“ÁˆŮ“I‘ŠŒÝě—p‚ˇ‚éˆę–{˝
DNAƒ‚ƒ`[ƒt‚Ě’Tő
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Žá™‘׌hA”öčČŒáA•ĐŽR •×
ƒ‚ƒfƒ‹×‹ŰCaulobacter cresentus‚É‚¨‚Ż‚é•ĄťIŒ‹“_ter‚Ć×–E•Ş—ô‘•’u‚Ě‹¤‹ÇÝ‚𒲐߂ˇ‚é
’`”’ŽżŠÔ‘ŠŒÝě—p‚̉đÍ
“ú–{ś‰ťŠw‰ď‹ăBŽx•”—á‰ďi‹ăB‘ĺŠwˆăŠw•” ‚TŒŽ23“úFŽăŠJĂj

’C–{—DAŽO‘PŒŤ–íA‰i“c–ƒ—œŽqA”öčČŒáA•ĐŽR •×
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”öčČŒáAŽá™‘׌hA•ĐŽR@•×
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ŽO‘PŒŤ–íA’C–{—DA”öčČŒáA‰i“c –ƒ—œŽqA•ĐŽR •×
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‹g“c—łŻA”öčČŒáAěăLéA•ĐŽR •×
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Žá™‘׌hA”öčČŒáA•ĐŽR@•×
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Ḡ‘^ŒłA”öčČŒáA•ĐŽR •×
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1–{˝DNA‚Ě”z—ń“ÁŤ‚̉đÍ
“ú–{ˆâ“`Šw‰ď‘ć92‰ń‘ĺ‰ď (‚­‚Ü‚ŕ‚ĆŒ§–ŻŒđ—Ź‰ďŠŮƒpƒŒƒA ‚XŒŽ16`18“úFŽăŠJĂj

‘ş‰Ş—´Ć, ”öčČŒá, •ĐŽR•×
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‘ć43‰ń “ú–{•ŞŽqś•¨Šw‰ď”N‰ďi12ŒŽ2“úi…j`4“úi‹ŕjFƒIƒ“ƒ‰ƒCƒ“ŠJĂ j

2019”N
Œ´’˜˜_•ś
Taniguchi, S., Kasho, K., Ozaki, S., and Katayama, T. (2019)
Escherichia coli CrfC protein, a nucleoid partition factor, localizes to nucleoid poles via the activities of specific nucleoid-associated proteins.
Front. Microbiol. 10: 72.
ƒI[ƒvƒ“ƒAƒNƒZƒX@doi: 10.3389/fmicb.2019.00072
F1000Prime„‘E˜_•ś(šš)‚É‘I‚΂ę‚Ü‚ľ‚˝i2019.3.19)

Kawakami, H., Muraoka, R., Ohashi, E, Kawabata, K., Kanamoto, S., Chichibu, T., Tsurimoto, T., and Katayama, T. (2019)
Specific basic patch-dependent multimerization of S. cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis
Genes Cells 24(9):608-618. doi: 10.1111/gtc.12710

Sugiyama, R., Kasho, K. (equal contributors), Miyoshi, K., Ozaki, S., Kagawa, W., Kurumizaka, H., and Katayama, T. (2019)
A novel mode of DnaA-DnaA interaction promotes ADP dissociation for reactivation of replication initiation activity
Nucleic Acids Res. 47(21):11209-11224
ƒI[ƒvƒ“ƒAƒNƒZƒX@doi: 10.1093/nar/gkz795
F1000Prime„‘E˜_•ś(šš)‚É‘I‚΂ę‚Ü‚ľ‚˝i2019.10.1)

Žĺ—vŠw‰ď”­•\
Katayama, T., Miyoshi, K., Hayashi, C., Yoshida, R., Sugiyama, R., Sakai, R., Sakiyama, Y., Kasho, K., Kawakami, H., Ozaki, S., and Nagata, M.
Dynamic mechanisms of higher-order complexes for replication initiation and regulation of the E. coli genome
‘ć92‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď (‰pŒęƒVƒ“ƒ|ƒWƒEƒ€uV‚ľ‚˘ƒQƒmƒ€‚ĚŽp‚Ć‚ť‚ĚˆŰŽ‹@\‚ĚƒtƒŒƒLƒVƒrƒŠƒeƒBv ƒI[ƒKƒiƒCƒU[FŒĂŒS–ƒŽq, łˆä‹v—YjiƒpƒVƒtƒBƒR‰Ą•l 9ŒŽ18`20“új

Katayama, T.
Regulatory systems and mechanisms for the replication initiator DnaA in Escherichia coli
‘ć42‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď (Workshop "New Frontiers in Studies of DNA Replication" organized by Masai, H. and Araki, H.)i•Ÿ‰Ş‘Ű‰ď‹cę 12ŒŽ3`6“új

Ozaki, S., Wakasugi, Y., and Katayama, T.
Identification and characterization of a novel DNA binding protein that colocalizes the chromosome replication terminus with cell division apparatus in Caulobacter crescentus
‘ć42‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď (Workshop "Frontiers in MIcrobial Cell Replication System" organized by Ozaki, S. and Takemoto, M.)i•Ÿ‰Ş‘Ű‰ď‹cę 12ŒŽ3`6“új

Kawakami, H., Muraoka, R., Kurihara, T., Chichibu, T., Kanamoto, S., Kawabata, K., Ohashi, E., Tsurimoto, T., and Katayama, T.
Single-stranded DNA binding of replication initiator in budding yeast
‘ć42‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď (Workshop "New Frontiers in Studies of DNA Replication" organized by Masai, H. and Araki, H.)i•Ÿ‰Ş‘Ű‰ď‹cę 12ŒŽ3`6“új

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ŒIŒ´‘ń–ç, ‘ş‰Ş—´Ć, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
^Šjś•¨ƒQƒmƒ€•Ąť‚Ě“ÁˆŮŤ‚đ•ŰŘ‚ˇ‚éAˆę–{˝DNA‚đ‰î‚ľ‚˝ƒQƒmƒ€ƒƒCƒh§ŒäŒn
‘ć13‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ď”N‰ďiŽń“s‘ĺŠw“Œ‹ž“ě‘ĺ‘ňƒLƒƒƒ“ƒpƒX ‚RŒŽ6`8“új

ŽO‘PŒŤ–í, ™ŽR —Č, ‰Áś˜aŽő, ”öčČŒá, •ĐŽR •×
‘ĺ’°‹ŰőF‘Ě‚Ě”ńƒR[ƒh—ĚˆćDARS‚É‚¨‚Ż‚éDnaA AAA+ƒhƒƒCƒ“‚̐V‚˝‚Č•Ą‡‘ĚŒ`Ź‚Ć“Ž‘Ô
2019”N“x“ú–{ś‰ťŠw‰ď‹ăBŽx•”—á‰ďi’ˇč‘ĺŠw •ś‹łƒLƒƒƒ“ƒpƒX ‚UŒŽ8`9“új

ŽO‘PŒŤ–í, ™ŽR —Č, ‰Áś˜aŽő, ”öčČŒá, •ĐŽR •×
”ńƒR[ƒhDNAˆöŽqDARS‚É‚¨‚Ż‚é•ĄťŠJŽn’`”’ŽżDnaA‚Ě•Ą‡‘ĚŒ`Ź‚ĆŠˆŤ‰ťƒƒJƒjƒYƒ€
“ú–{ˆâ“`Šw‰ď‘ć91‰ń‘ĺ‰ď (•Ÿˆä‘ĺŠw•ś‹žƒLƒƒƒ“ƒpƒX 9ŒŽ11“ú`13“ú)

Nagata, M., Sakiyama, Y., Hayashi, C., Ozaki, S., and Katayama, T.
Analysis for mechanisms of DnaB helicase loading by specific DnaA subcomplexes for bidirectional replication of the E. coli chromosome
‘ć92‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ďiŒű“Ş”­•\jiƒpƒVƒtƒBƒR‰Ą•l 9ŒŽ18`20“új

2018”N
‘ŕ
ěăLé, •ĐŽR •×
^Šj×–EƒQƒmƒ€‚É‚¨‚Ż‚é•Ąť‹N“_’T‚ľ‚Ě•ŞŽq‹@\
‹ăB‘ĺŠwƒAƒCƒ\ƒg[ƒv“‡ˆŔ‘SŠÇ—ƒZƒ“ƒ^[, 2018, Vol. 3, pp7-8
Œ´’˜˜_•ś
Sakiyama, Y., Nishimura, M. (equal contributors), Hayashi, C., Akama, Y., Ozaki, S., and Katayama, T. (2018)
The DnaA AAA+ domain His136 residue directs DnaB replicative helicase to the unwound region of the replication origin, oriC.
Front. Microbiol. 9: 2017.
ƒI[ƒvƒ“ƒAƒNƒZƒX@doi: 10.3389/fmicb.2018.02017
Žĺ—vŠw‰ď”­•\
Katayama, T., Kasho, K., Sakiyama, Y., and Kawakami, H.
Mechanisms of DnaA assembly at the replication origin and in vitro reconstitution of the DnaA cycle, which regulates the initiation of chromosomal replication in E. coli
The 6th International Symposium on Dynamical Ordering of Biomolecular Systems for Creation of Integrated Functions (Hamamatsu Act Tower, Japan, Jan. 20-21, 2018)

Kawakami, H., Chichibu, T., Kanamoto, S., Ohashi, E., Tsurimoto, T., and Katayama, T.
ssDNA-related multifaceted safeguards in ORC dynamics govern specific replication origin selection
EMBO | EMBL Symposia "DNA Replication: From Basic Biology to Disease" (EMBL Heidelberg, Germany, May 7-10, 2018)

Katayama, T., Sakiyama, Y., Noguchi, Y., Kawakami, H., and Ozaki, S.
Central dynamics of DnaA oligomers in the initiation complex for chromosomal replication in Escherichia coli
EMBO Workshop "DNA replication, chromosome segregation and fate decisions" (Kyllini, Greece, September 17-21, 2018)

Katayama, T., Sakiyama, Y., Noguchi, Y., Kasho, K., Kawakami, H., and Ozaki, S.
Central dynamics of DnaA-oriC complexes in DNA unwinding for initiation of chromosomal replication in E. coli: ssDUE-recruitment mechanism
The 11th 3R(Replication, Repair, Recombination)+3C(Chromosome, Chromatin, Cell cycle Sympojium (Kanazawa, Japan, November 12-16, 2018) (Oral presentation)

Kawakami, H., Chichibu, T., Kanamoto, S., Kurihara, T., Muraoka, R., Ohashi, E., Tsurimoto, T., and Katayama, T.
ssDNA as a dynamic and genome-wide mediator governing specificity of eukaryotic replication origin selection
The 11th 3R(Replication, Repair, Recombination)+3C(Chromosome, Chromatin, Cell cycle Sympojium (Kanazawa, Japan, November 12-16, 2018)

Miyoshi, K., Kasho, K., Fujimitsu, K., Ozaki, S., and Katayama, T.
The scheduled replication initiation is regulated by timely IHF binding to specific chromosomal loci for activation and inactivation of the initiator DnaA in Escherichia coli
The 11th 3R(Replication, Repair, Recombination)+3C(Chromosome, Chromatin, Cell cycle Sympojium (Kanazawa, Japan, November 12-16, 2018)

Hayashi, C., Sakiyama, Y., Nishimura, M,. Akama, Y., Ozaki, S., and Katayama, T.
Role for the DnaA AAA+ domain N-terminus in interaction with DnaB helicase for replication initiation
The 11th 3R(Replication, Repair, Recombination)+3C(Chromosome, Chromatin, Cell cycle Sympojium (Kanazawa, Japan, November 12-16, 2018)

Katayama, T.
Mechanisms and regulations in the initiator DnaA and the initiation complex
OKAZAKI Fragment Memorial Symposium: Celebrating the 50th anniversary of the discontinuous DNA replication model (Sakata and Hirata Hall, Nagoya University, December 17-18, 2018) (Invited speaker)

–ěŒű‘דż, •ĐŽR •×
‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťŠJŽn‚ɑ΂ˇ‚éV‚˝‚Ȑ§ŒäƒVƒXƒeƒ€FDnaBƒwƒŠƒJ[ƒ[‘•’…‚đ•W“I‚Ć‚ˇ‚éV‹KˆöŽq
‘ć12‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ďi‹ž“s‘ĺŠwŒjƒLƒƒƒ“ƒpƒX 3ŒŽ5`7“új

—Ń çq, ‹{čŒb—˘‰Á, ź‘şš—m, ”öčČŒá, •ĐŽR •×
‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťƒwƒŠƒJ[ƒ[DnaB‚É‚¨‚Ż‚é•ĄťŠJŽnƒ^ƒ“ƒpƒNŽżDnaA‚Ć‚Ě‘ŠŒÝě—p‚ɏd—v‚ČƒAƒ~ƒmŽ_ŽcŠî‚Ě’Tő
‘ć15‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ďiŽRŒ`Œ§“ě—zŽs 5ŒŽ24`25“újƒ|ƒXƒ^[”­•\ÜiŠw•”śE”ŽŽm‰Ű’ö‘OŠújŽóÜ

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ŒIŒ´ ‘ń, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
•Ąť‹N“_“ńd˝DNA‚Ě”FŽŻ‰ß’ö‚É‚¨‚Ż‚éˆę–{˝DNA‚Ě–đŠ„
•˝Ź 30”N“x“ú–{ś‰ťŠw‰ď‹ăBŽx•”—á‰ď (‹ăB‘ĺŠw”noƒLƒƒƒ“ƒpƒX 6ŒŽ30“ú`7ŒŽ1“új

”öčČŒá, Christian, A., and Urs, J.
The role of the second messenger signalling for coordinating chromosome replication in time and space
“ú–{ˆâ“`Šw‰ď ‘ć90‰ń‘ĺ‰ď @ƒ[ƒNƒVƒ‡ƒbƒvu‘˝—l‚Čƒ‚ƒfƒ‹Œ´Šjś•¨‚̉đÍ‚Š‚猊‚Ś‚Ä‚­‚éˆâ“`î•ń•ĄťEŒpł‚Ě‹¤’ĘŒ´—‚Ć‘˝—lŤiŔ’ˇF”öčČŒá, “n•Ó ’qjv(“ޗǐć’[‘ĺ 9ŒŽ19`22“ú)

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“ú–{ˆâ“`Šw‰ď ‘ć90‰ń‘ĺ‰ď (“ޗǐć’[‘ĺ 9ŒŽ19`22“ú)

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ŒIŒ´‘ń–ç, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
ORC‚Ě•Ąť‹N“_Œ‹‡”\‚đ•ŰŘ‚ˇ‚é‚˝‚ß‚Ěˆę–{˝Œ‹‡§ŒäŒn
‘ć91‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď@ƒVƒ“ƒ|ƒWƒEƒ€uˆâ“`î•ń‚ĚˆŰŽŒpł‚É‚¨‚Ż‚éƒ~ƒNƒ‚Ćƒ}ƒNƒ‚Ě“‡“I—‰đFś‰ťŠw‚̐V‚˝‚Č’§íviƒI[ƒKƒiƒCƒU[FěăLé, łˆä‹v—Yji‹ž“s‘Ű‰ď‹cę 9ŒŽ24`26“új

•ĐŽR •×
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‘ć41‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒ[ƒNƒVƒ‡ƒbƒvu3RƒVƒXƒeƒ€‚ƍ‚ŽŸ•Ą‡‘Ě“Ž‘Ô‚Ě–@‘ĽŤ‚Ć‘˝—lŤv(ƒI[ƒKƒiƒCƒU[: •ĐŽR •×, Šâč”ŽŽj) @iƒpƒVƒtƒBƒR‰Ą•l 11ŒŽ28`30“új

”öčČŒá, Urs, J., Žá™‘׌h, •ĐŽR •×
The role of the bacterial second messenger signaling for chromosome segregation dynamics in Caulobacter crescentus
‘ć41‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒ[ƒNƒVƒ‡ƒbƒvu”÷ś•¨‚Ě‘B‚Ć‚Ó‚é‚Ü‚˘‚Ě•ĄŽGŤF‘˝—l‚Čƒ‚ƒfƒ‹”÷ś•¨Œn‚Š‚ç“ž’B‚ˇ‚éV‚˝‚Č—‰đviƒI[ƒKƒiƒCƒU[: ”öčČŒá, ‰Á“Ą ßjiƒpƒVƒtƒBƒR‰Ą•l 11ŒŽ28`30“új

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ŒIŒ´‘ń–ç, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
•Ąť‹N“_‚Ě“ÁˆŮ“I”FŽŻ‚đ•ŰŘ‚ˇ‚éA“Ž“I‚Š‚ƒQƒmƒ€ƒƒCƒh‚ČORCEˆę–{˝Œ‹‡§Œä
‘ć41‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒ[ƒNƒVƒ‡ƒbƒvuŒŠ‚Ś‚Ä‚Ť‚˝IƒtƒŒƒLƒVƒuƒ‹‚Ĺƒ_ƒCƒiƒ~ƒbƒN‚ČƒQƒmƒ€
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2017”N
‘ŕ
Katayama, T.
Initiation of DNA replication at the chromosomal origin of E. coli, oriC
A chapter in the book entitled 'DNA Replicationn: From Old Principles to New Discovery' (Hisao Masai and Marco Foiani, Eds): Adv Exp Med Biol.1042, SpringerNature pp 79-98.
doi: 10.1007/978-981-10-6955-0_4

Katayama, T., Kasho, K., and Kawakami, H. (2017)
The DnaA cycle in Escherichia coli: activation, function, and inactivation of the initiator protein
Front. Microbiol. 8:2496. doi: 10.3389/fmicb.2017.02496

Œ´’˜˜_•ś
Sakiyama, Y., Kasho, K., Noguchi, Y., Kawakami, H., and Katayama, T. (2017)
Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli
Nucleic Acids Res. 45(21); 12354-12373.
ƒI[ƒvƒ“ƒAƒNƒZƒX https://doi.org/10.1093/nar/gkx914

Kasho, K., Tanaka, H., Sakai, R., and Katayama, T. (2017)
Cooperative DnaA binding to the negatively supercoiled datA locus stimulates DnaA-ATP hydrolysis
J. Biol. Chem. 292(4);1251-1266. doi: 10.1074/jbc.M116.762815

Su'etsugu, M., Takada, H., Katayama, T., and Tsujimoto, H. (2017)
Exponential propagation of large circular DNA by reconstitution of a chromosome-replication cycle
Nucleic Acids Res. 45(20);11525-11534.
ƒI[ƒvƒ“ƒAƒNƒZƒX https://doi.org/10.1093/nar/gkx822
F1000Prime„‘E˜_•ś

Abe, Y., Shioi, S., Kita, S., Nakata, H., Maenaka, K., Kohda, D., Katayama, T., and Ueda, T. (2017)
X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation.
FEBS Lett. 591(22);3805-3816. doi: 10.1002/1873-3468.12892

Zhang, J., Taniguchi, S., Ito, H., Iiyama, K., Hino, M., Katayama, T., and Kimura, M. (2017)
Expression of a Vibrio parahaemolyticus toxin in Escherichia coli results in chromosomal DNA degradation
Biosci. Biotechnol. Biochem. 81(10); 1937-1940 doi: 10.1080/09168451.2017.1347486.

Žĺ—vŠw‰ď”­•\
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“ú–{ˆâ“`Šw‰ď‘ć89‰ń‘ĺ‰ďi‰ŞŽR‘ĺŠw 9ŒŽ13-16“új –ŘŒ´ÜŽóÜu‰‰

‰Áś˜aŽőA‘哇 ‘ńA•ĐŽR •×
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“ú–{ˆâ“`Šw‰ď‘ć89‰ń‘ĺ‰ďi‰ŞŽR‘ĺŠw 9ŒŽ13-16“új

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ěăLé, çX•z‘s—z, ě”¨Œ’‘ž, ‹ŕ–{Ë‘ž, ‘ĺ‹´ ‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×,
ORC‚Ěˆę–{˝DNAŒ‹‡”\‚đ‰î‚ľ‚˝‘o•űŒü‹@”\“Ž‘Ԑ§Œä
‘ć24‰ńDNA•ĄťE‘gŠˇ‚ŚEC•œƒ[ƒNƒVƒ‡ƒbƒvi’ˇ—Çě‘Ű‰ď‹cę 11ŒŽ27-29“új

’JŒűŽŃ‹P, ‰Áś ˜aŽő, •ĐŽR •×,
‘ĺ’°‹ŰV‹K•Ş”zˆöŽq CrfC ‚̐őF‘̍\‘˘‚ɉž‚ś‚˝‹ÇÝŤ§Œä—lŽŽ‚̉đÍ
‘ć24‰ńDNA•ĄťE‘gŠˇ‚ŚEC•œƒ[ƒNƒVƒ‡ƒbƒvi’ˇ—Çě‘Ű‰ď‹cę 11ŒŽ27-29“új

•ĐŽR •×, ‰Áś ˜aŽő, čŽR—F—˘, Žđˆä—˛ŽŠ, ™ŽR —Č, ˆäă—SŠó], ěăLé,
‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťŠJŽn‚É‚¨‚Ż‚éDnaAƒ^ƒ“ƒpƒNŽż‚Ć‚ť‚̐§ŒäDNAˆöŽqDARS2‚¨‚ć‚ŃdatA‚Ě•ŞŽq“Ž‘Ô‹@\,
2017”Nś–˝‰ČŠwŒnŠw‰ď‡“Ż”NŽŸ‘ĺ‰ď@ƒ[ƒNƒVƒ‡ƒbƒvuŒ´Šj×–EƒQƒmƒ€“Ž‘Ԃ̐V‚˝‚ČŠî‘bŒ¤‹†‚Ě“WŠJviƒI[ƒKƒiƒCƒU[F•ĐŽR •×, Î–ě—Ǐƒj, i_ŒË‘Ű‰ď‹cę 12ŒŽ6-9 “új

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ‘ĺ‹´ ‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×,
•Ąť‹N“_”FŽŻ’`”’ŽżORC‚É‚¨‚Ż‚éˆę–{˝DNAŒ‹‡ƒ‚ƒ`[ƒt‚Ě–đŠ„,
2017”Nś–˝‰ČŠwŒnŠw‰ď‡“Ż”NŽŸ‘ĺ‰ďi_ŒË‘Ű‰ď‹cę 12ŒŽ6-9 “új

™ŽR —Č, ‰Áś˜aŽő, •ĐŽR •×,
•ĄťŠJŽnƒ^ƒ“ƒpƒNŽżDnaA‚đŠˆŤ‰ť‚ˇ‚é“ÁˆŮ“I‚ČDNA”z—ńDARS (DnaA reactivating sequence) ‚É‚¨‚Ż‚éDnaAŠÔ‘ŠŒÝě—p—lŽŽ‚̉đÍ
2017”Nś–˝‰ČŠwŒnŠw‰ď‡“Ż”NŽŸ‘ĺ‰ďi_ŒË‘Ű‰ď‹cę 12ŒŽ6-9 “új

ě”¨Œ’‘ž, çX•z‘s—z, ěăLé, ‘ĺ‹´ ‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×,
^Šjś•¨‚Ě•ĄťŠJŽn‚É•K{‚ČORC‚ĆCdc6‚É‚¨‚Ż‚é“ńd˝‚Č‚ç‚Ń‚Éˆę–{˝DNAŒ‹‡•”ˆĘ‚Ě’Tő
2017”Nś–˝‰ČŠwŒnŠw‰ď‡“Ż”NŽŸ‘ĺ‰ďi_ŒË‘Ű‰ď‹cę 12ŒŽ6-9 “új

(ŽQlj
”öčČŒá, Jenel, U. iBasel Univ.j
ƒoƒNƒeƒŠƒA‚ĚƒQƒmƒ€•Ąť‚đŽüŠú“I‚É‹ě“Ž‚ˇ‚é’á•ŞŽqƒVƒOƒiƒŠƒ“ƒO‚Ě•ŞŽq‹@\
‘ć24‰ńDNA•ĄťE‘gŠˇ‚ŚEC•œƒ[ƒNƒVƒ‡ƒbƒvi’ˇ—Çě‘Ű‰ď‹cę 11ŒŽ27-29“új

”öčČŒá, Lori. C., Dubey, B., Schirmer, T., Jenel, U. iBasel Univ.j
ƒZƒJƒ“ƒhƒƒbƒZƒ“ƒWƒƒ[cyclic-di-GMP‚͍זEŽüŠúƒLƒi[ƒ[‚𒲐߂ľAőF‘Ě•Ąť‚đ‹ě“Ž‚ˇ‚é
2017”Nś–˝‰ČŠwŒnŠw‰ď‡“Ż”NŽŸ‘ĺ‰ď@ƒ[ƒNƒVƒ‡ƒbƒvuŒ´Šj×–EƒQƒmƒ€“Ž‘Ԃ̐V‚˝‚ČŠî‘bŒ¤‹†‚Ě“WŠJviƒI[ƒKƒiƒCƒU[F•ĐŽR •×, Î–ě—Ǐƒj, i_ŒË‘Ű‰ď‹cę 12ŒŽ6-9 “új

2016”N
Œ´’˜˜_•ś
Shimizu, M., Noguchi, Y., Sakiyama, Y., Kawakami, H., Katayama, T.*, and Takada, S.* (*Co-corresponding authors) (2016)
Near-atomic structural model for bacterial DNA replication initiation complex and its functional insights
Proc. Natl. Acad. Sci. USA, 113(50); E8021-E8030 doi:10.1073/pnas.1609649113

Noguchi, Y. and Katayama, T. (2016)
The Escherichia coli cryptic prophage protein YfdR binds to DnaA and initiation of chromosomal replication is inhibited by overexpression of the gene cluster yfdQ-yfdR-yfdS-yfdT
Front. Microbiol. 7; 239. (21 pages) doi: 10.3389/fmicb.2016.00239

Kawakami, H., Ohashi, E., Tsurimoto, T., and Katayama, T. (2016)
Rapid purification and characterization of mutant origin recognition complexes in Saccharomyces cerevisiae
Front. Microbiol. 7; 521. (9 pages ) doi: 10.3389/fmicb.2016.00521

Inoue, Y., Tanaka, H., Kasho, K. (equal contributors), Fujimitsu, K., Oshima, T., and Katayama, T. (2016)
Chromosomal location of the DnaA-reactivating sequence DARS2 is important to regulate timely initiation of DNA replication in Escherichia coli
Genes Cells 21(9); 1015-1023. doi: 10.1111/gtc.12395

Lai, P. J., Lim, C. T., Le, H. P., Katayama, T., Leach, D. R. F., Furukohri, A. and Maki, H. (2016)
Long inverted repeat transiently stalls DNA replication by forming hairpin structures on both leading and lagging strands
Genes Cells 21(2); 136-145. doi: 10.1111/gtc.12326

Abe, Y., Fujisaki, N., Miyoshi, T., Watanabe, N., Katayama, T., and Ueda, T. (2016)
Functional analysis of CedA based on its structure: residues important in binding of DNA and RNA polymerase and in the cell division regulation
J. Biochem. 159(2); 217-223. doi:10.1093/jb/mvv096

Gatanaga, C., Yang, B., Inadomi, Y., Usui, K., Ota, C., Katayama, T., Suemune, H., and Aso, M. (2016)
Site-specific turn-on fluorescent labeling of DNA-interacting protein using oligodeoxynucleotides that modify lysines to produce 5,6-dimethoxy 3-methyleneisoindolin-1-one.
ACS Chem. Biol. 11(8); 2216-2221.

Žĺ—vŠw‰ď”­•\
•ĐŽR •×, ‰Áś˜aŽő, ‘哇 ‘ń
Šj—l‘ĚˆöŽqIHF‚É‚ć‚é•ĄťŠJŽn§ŒäƒQƒmƒ€ˆöŽq‚Ě“‡§Œä
‘ć10‰ń“ú–{ƒQƒmƒ€”÷ś•¨Šw‰ď”N‰ď (“Œ‹žH‹Ć‘ĺŠw ‘剪ŽRƒLƒƒƒ“ƒpƒX 3ŒŽ4`6“ú)

ěăLé, ‘ĺ‹´‰pŽĄ, ‹ŕ–{Ë‘ž, ’Ţ–{•qŽ÷, •ĐŽR •×
o‰čy•ęORC•Ą‡‘Ě‚É‚ć‚éőF‘Ě”FŽŻ‹@\‚Ć‚ť‚Ě‘˝—lŤ
•˝Ź28”N“x“ú–{ś‰ťŠw‰ď‹ăBŽx•”—á‰ďiŽ­Ž™“‡‘ĺŠwŒSŒłƒLƒƒƒ“ƒpƒX 5ŒŽ14`15“új

‰Áś˜aŽő, “c’†GK, Žđˆä—˛“ń, •ĐŽR •×
‘ĺ’°‹ŰőF‘ĚdatA”z—ń‚É‚ć‚é•ĄťŠJŽn’`”’ŽżDnaA•sŠˆŤ‰ť‹@\‚ĚDNA’´‚ç‚š‚ń‚ɉž‚ś‚˝§Œä‚̉đÍ
•˝Ź28”N“x“ú–{ś‰ťŠw‰ď‹ăBŽx•”—á‰ďiŽ­Ž™“‡‘ĺŠwŒSŒłƒLƒƒƒ“ƒpƒX 5ŒŽ14`15“új

’JŒűŽŃ‹P, ‰Áś˜aŽő, •ĐŽR •×
×–E‹É‹ß–T‚ɋǍ݂ˇ‚éCrfC‚¨‚ć‚ŃŠj—l‘Ě‚Ě×–E“ŕ‹ÇÝŤ‰đÍ
‘ć13‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ďiƒOƒŠ[ƒ“ƒsƒA“ěˆ˘‘h 6ŒŽ2`3“új

•ĐŽR •×
•ĄťŠJŽn’`”’ŽżDnaA‚ɑ΂ˇ‚鐧ŒäŒn‚ĚŽŠ—Ľ“I˜A“ŽƒVƒXƒeƒ€‚Ě‘nś‚Ć“Ž‘ÔŒ´—‚̉đÍ
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•ĐŽR •×@
‘ĺ’°‹Ű‚̐őF‘Ě•Ąť‹N“_oriC‚É‚¨‚Ż‚éDnaA•Ą‡‘Ě‚Ěƒ_ƒCƒiƒ~ƒNƒX
“ú–{i‰ťŠw‰ď ‘ć18‰ń“Œ‹ž‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvuś•¨i‰ť‚É”ş‚¤DNA•Ąť‘•’u‚ĚDynamicsvi“Œ‹žH‹Ć‘ĺŠw‘剪ŽRƒLƒƒƒ“ƒpƒX 8ŒŽ25`28“új

čŽR —F—˘, –ěŒű ‘דż, ěă Lé, •ĐŽR •×
‘ĺ’°‹ŰőF‘Ě‚Ě•Ąť‹N“_oriCă‚ĹŒ`Ź‚ł‚ę‚éDnaA‘˝—Ę‘Ě‚Ě‹@”\“Ž‘Ԃ̉đ–ž
“ú–{ˆâ“`Šw‰ď‘ć88‰ń‘ĺ‰ď ƒvƒŒƒiƒŠ[ƒ[ƒNƒVƒ‡ƒbƒv --đ”N‚ĚBPÜŽóÜu‰‰‚Š‚ç-- i“ú–{‘ĺŠw‘ŰŠÖŒWŠw•” ŽO“‡‰w–kŒűZŽÉ 9ŒŽ7`10“új

‰Áś˜aŽő, ‘哇 ‘ń, •ĐŽR •×
Šj—l‘Ě’`”’ŽżIHF‚Ć“ÁˆŮ“I‚ČDNA•”ˆĘ‚Ć‚Ě•Ą‡‘ĚŒ`ŹE‰đ—Ł‚É‚ć‚é•ĄťŠJŽnƒ^ƒCƒ~ƒ“ƒO§Œä
“ú–{ˆâ“`Šw‰ď‘ć88‰ń‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvuƒoƒNƒeƒŠƒA‚Ě‘SƒQƒmƒ€‰đÍ‚Š‚猊‚Ś‚Ä‚Ť‚˝V‚˝‚Čˆâ“`Žq‚Ć’`”’Žż‚Ě•ŞŽq“Ž‘ԁvi˘˜bl ‘哇 ‘ńA•ĐŽR •×ji“ú–{‘ĺŠw‘ŰŠÖŒWŠw•” ŽO“‡‰w–kŒűZŽÉ 9ŒŽ7`10“új

–ěŒű‘דż, •ĐŽR •×
‘ĺ’°‹ŰK12Š”ƒQƒmƒ€‚̐öÝŤƒvƒƒtƒ@[ƒW‚ĚYfdR’`”’Žż‚͐őF‘Ě•ĄťŠJŽn’`”’ŽżDnaA‚Ć‘ŠŒÝě—p‚ˇ‚é
“ú–{ˆâ“`Šw‰ď‘ć88‰ń‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvu•aŒ´”÷ś•¨ƒQƒmƒ€‚Ě•Ąť‚Ć•aŒ´Ťvi˘˜bl _čGŽkji“ú–{‘ĺŠw‘ŰŠÖŒWŠw•” ŽO“‡‰w–kŒűZŽÉ 9ŒŽ7`10“új

•ĐŽR •×, čŽR—F—˘, ÔŠÔ—E‰î, –ěŒű‘דż, ěăLé, ‰Áś˜aŽő
‘ĺ’°‹Ű‚Ě•ĄťŠJŽn•Ą‡‘Ě‚É‚¨‚Ż‚é‚Qd˝DNAŠJ—ô‚ĆƒwƒŠƒJ[ƒ[‘ŠŒÝě—p‚Ě•ŞŽq‹@\
‘ć89‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď ƒVƒ“ƒ|ƒWƒEƒ€uƒQƒmƒ€‚ĚˆŰŽ‚ĆŒpł‚đ§Œä‚ˇ‚éƒ^ƒ“ƒpƒNŽż‚ĆŠjŽ_‚Ě‘ŠŒÝě—pv(ƒI[ƒKƒiƒCƒU[Fłˆä ‹v—YA•ĐŽR •×) (“Œ–k‘ĺŠwě“ŕ–kƒLƒƒƒ“ƒpƒX 9ŒŽ25`27“új

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ě”¨Œ’‘ž, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
^Šjś•¨‚Ě•Ąť‹N“_”FŽŻ’`”’ŽżORC‚É‚ć‚é‘˝Šp“I‚ČDNA’Tő”FŽŻ‹@\
‘ć89‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď (“Œ–k‘ĺŠwě“ŕ–kƒLƒƒƒ“ƒpƒX 9ŒŽ25`27“új

Katayama, T., Sakiyama, Y., Noguchi, Y., and Kawakami, H.
Structure, Mechanism and Regulation of Escherichia coli Replication Initiation Complexes in DNA Unwinding
The 10th 3R Symposium (Matsue, Nov 13-17)

Kasho, K., Inoue, Y., Oshima, T., Fujimitsu, K., and Katayama, T.
Regulation of timely replication initiation by a nucleoid protein IHF on DnaA activating and inactivating DNA elements, DARS2 and datA in Escherichia coli
The 10th 3R Symposium (Matsue, Nov 13-17)

Kawakami, H., Chichibu, T., Ohashi, E., Kanamoto, S., Tsurimoto, T. and Katayama, T.
Multifaceted approach of Orc1 to DNA is the primary determinant of specific recognition of replication origins by ORC
The 10th 3R Symposium (Matsue, Nov 13-17)

Sakiyama, Y., Noguchi, Y., Kawakami, H., and Katayama, T.
Functional dynamics of replication initiation complex in Escherichia coli
The 10th 3R Symposium (Matsue, Nov 13-17)

Taniguchi, S., Kasho, K., and Katayama, T.
Analysis for the subcellular localization of E. coli dynamin-like protein CrfC, a novel factor in chromosome positioning
The 10th 3R Symposium (Matsue, Nov 13-17)

•ĐŽR •×, ‰Áś˜aŽő, čŽR—F—˘, ÔŠÔ—E‰î, ˆäă—SŠó], Žđˆä—˛ŽŠ, ™ŽR —Č, ěăLé
‘ĺ’°‹Ű‚ĚoriC‚É‚¨‚Ż‚é•ĄťŠJŽn‚Ć‚ť‚̐§Œä‚Ě‚˝‚ß•ĄťŠJŽnˆöŽqDnaAƒ^ƒ“ƒpƒNŽż‚ލ\’z‚ˇ‚鍂ŽŸ•Ą‡‘Ě‚Ě•ŞŽq‹@\
‘ć39‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď ƒVƒ“ƒ|ƒWƒEƒ€uőF‘Ě•Ąť•Ą‡‘Ě‚ĚŒ`Ź‚ƍ\‘˘•Ď‰ť‚Ě•ŞŽq‹@\‚Ć‚ť‚̐§ŒäviƒI[ƒKƒiƒCƒU[F•ĐŽR •×, ’Ţ–{•qŽ÷j‘ć39‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďiƒpƒVƒtƒBƒR‰Ą•l 11ŒŽ30“ú`12ŒŽ2“új

´…Ť—T, –ěŒű‘דż, čŽR—F—˘, ěăLé, •ĐŽR •×, ‚“c ˛“ń
×‹ŰDNA•ĄťŠJŽn•Ą‡‘Ě‚Ě‹ßŒ´Žq\‘˘ƒ‚ƒfƒ‹‚Ć‹@”\‰đÍ
‘ć39‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď ƒVƒ“ƒ|ƒWƒEƒ€uőF‘Ě•Ąť•Ą‡‘Ě‚ĚŒ`Ź‚ƍ\‘˘•Ď‰ť‚Ě•ŞŽq‹@\‚Ć‚ť‚̐§ŒäviƒI[ƒKƒiƒCƒU[F•ĐŽR •×, ’Ţ–{•qŽ÷j‘ć39‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďiƒpƒVƒtƒBƒR‰Ą•l 11ŒŽ30“ú`12ŒŽ2“új

ěăLé, çX•z‘s—z, ‹ŕ–{Ë‘ž, ‘ĺ‹´‰pŽĄ, ’Ţ–{•qŽ÷, •ĐŽR •×
•Ąť‹N“_”FŽŻ’`”’ŽżORC‚Ěˆę–{˝DNAŒ‹‡”\‚Ɛś•¨ƒhƒƒCƒ“‚đ’´‚Ś‚˝•Ű‘śŤ
‘ć39‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď iƒpƒVƒtƒBƒR‰Ą•l 11ŒŽ30“ú`12ŒŽ2“új

2015”N
Œ´’˜˜_•ś
Noguchi, Y., Sakiyama, Y., Kawakami, H., and Katayama, T. (2015)
The Arg fingers of key DnaA protomers are oriented inward within the replication origin oriC and stimulate DnaA subcomplexes in the initiation complex
J. Biol. Chem. 290(33);20295-20312 doi: 10.1074/jbc.M115.662601

Kawakami, H., Ohashi, E., Kanamoto, S., Tsurimoto, T., and Katayama, T. (2015)
Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues
Sci. Rep. 5; 14929 (14 pages)

Le, H. P., Masuda, Y., Tsurimoto, T., Maki, S., Katayama, T., Furukohri, A., and Maki, H. (2015)
Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork
Genes Cells 20(10); 817-833 doi: 10.1111/gtc.12275

Aramaki, T., Abe, Y., Furutani, K., Katayama, T., and Ueda, T. (2015)
Basic and aromatic residues in the C-terminal domain of PriC are involved in ssDNA and SSB binding
J. Biochem. 157(6);529-537 doi: 10.1093/jb/mvv014

Yang, B., Jinnouchi, A., Usui, K., Katayama, T., Fujii, M., Suemune, H., and Aso, M. (2015)
Bioconjugation of oligodeoxynucleotides carrying 1.4-decarbonyl groups via reductive amination with lysine residues
Bioconjugate Chem. 26, 1830-1838

Žĺ—vŠw‰ď”­•\
’JŒűŽŃ‹P, –ěŒű‘דż, ‰Áś˜aŽő, •ĐŽR@•×
‘ĺ’°‹Ű‚̐VśDNA˝‚̐ڒ…‚¨‚ć‚Ń‹Ď“™•Ş”z‚đŽx‚Ś‚éƒ_ƒCƒiƒ~ƒ“—l’`”’ŽżCrfC‚ĚC––’[—Ěˆć‚Ě‹@”\‰đÍ,
2015”N ś‘̉^“Ž‡“Ż”ljď‹c (ŠwK‰@‘ĺ 1ŒŽ7`9“új

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‘ĺ’°‹ŰoriC‚Ĺ‚Ě•ĄťŠJŽn‚É•K—v‚ČDNAŠJ—ô•Ą‡‘Ě‚Ě’†•\‘˘‚̉đ–ž, Best PapersÜ
“ú–{ˆâ“`Šw‰ď‘ć87‰ń‘ĺ‰ďi“Œ–k‘ĺŠw ‚XŒŽ24`26“új

‰Áś˜aŽő, ‘ş’JŽüŒĺ, –Ń’J‘şŒŤŽi, •ĐŽR@•×
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‰Áś˜aŽő, “c’†GK, •ĐŽR •×
‘ĺ’°‹ŰőF‘ĚdatA—Ěˆć‚É‚ć‚é•ĄťŠJŽn’`”’ŽżDnaA‚Ě•sŠˆŤ‰ť‹@\‚ÍDNA’´‚ç‚š‚ń\‘˘ˆË‘ś“I‚ɐ§Œä‚ł‚ę‚é
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2014”N
‘ŕ
•ĐŽR@•×
•ĄťŒă‚ĚDNA‚̐ڒ…‚Ć•Ş”z‚đ§Œä‚ˇ‚éV‹K‚Čƒ^ƒ“ƒpƒNŽżˆöŽq
ƒtƒ@ƒ‹ƒ}ƒVƒA, 51(2):99-103
Œ´’˜˜_•ś
Kasho, K., Fujimitsu, K., Matoba, T., Oshima,T., and Katayama, T. (2014)
Timely binding of IHF and Fis to DARS2 regulates ATP-DnaA production and replication initiation
Nucleic Acids Res. 42(21):13134-13149 doi: 10.1093/nar/gku1051
“ŕ—eĐ‰îƒy[ƒW

Ikeda, M., Furukohri, A., Philippin, G., Loechler, E., Tatsumi-Akiyama, M., Katayama, T., Fuchs, R.P., and Maki, H. (2014)
DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N2-dG adducts
Nucleic Acids Res. 42(13):8461-8472

Fujiyama, S., Abe, Y., Takenawa, T., Aramaki, T., Shioi, S., Katayama, T., and Ueda, T. (2014)
Involvement of histidine in complex formation of PriB and single-stranded DNA
Biochim. Biophys. Acta. 1844(2):299-307.

Fujiyama, S., Abe, Y., Tani, J., Urabe, M., Sato, K., Aramaki, T., Katayama, T., and Ueda, T. (2014)
Structure and mechanism of the primosome protein DnaT-functional structures for homotrimerization, dissociation of ssDNA from the PriB-ssDNA complex, and formation of the DnaT-ssDNA complex
FEBS J. 281(23):5356-5370.

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•ĐŽR •×, ”öčČŒá, ěăLé, –ěŒű‘דż, ‰Áś˜aŽő, ‰i“cŹ“, čŽR—F—˘, ’JŒűŽŃ‹P
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2014”N ś‘̉^“Ž‡“Ż”ljď‹ciç—t‘ĺ 2014”N‚PŒŽ10`12“új

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‘ĺ’°‹ŰőF‘ĚDNA‚̐ڒ…‚Ć•Ş”z‚É•K—v‚ȐV‹KDNA-’`”’Žż•Ą‡‘Ě
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čŽR—F—˘, –ěŒű‘דż, ěăLé, •ĐŽR •×
•Ąť‹N“_‚ĹŒ`Ź‚ł‚ę‚é“ńd˝ DNA ŠJ—ô•Ą‡‘Ě‚Ě‹@”\\‘˘‚̉đÍ
‘ć 11 ‰ń 21 ˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď (ˇ‰ŞŽs 2014”N6ŒŽ5~6“új

“y“cˆ¤ŠC, ěăLé, ––ŽŸłK, •ĐŽR •×
‘ĺ’°‹ŰőF‘Ě‚Ěˆâ“`ŽqŠÔ—Ěˆć‚É‘śÝ‚ˇ‚é’ˇ˝‹t•űŒü”˝•œ”z—ń ELIXIR ‚Ě‹@”\‰đÍ
‘ć 11 ‰ń 21 ˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď (ˇ‰ŞŽs 2014”N6ŒŽ5~6“új

•ĐŽR •×, ’JŒűŽŃ‹P, –ěŒű‘דż, čŽR—F—˘, ‰i“cŹ“, ‰Áś˜aŽő, ěăLé, áÁ–ö_‘ž
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2014”NVŠwp—Ěˆću‰^“Ž’´•ŞŽq‚ސD‚č‚Č‚ˇ’˛˜a‚Ć‘˝—lŤv‘ć“ń‰ń‘S‘̉ď‹c (ˆŽěŽs 2014”N‚UŒŽ16~18“új

ěăLé, ‘ĺ‹´‰pŽĄ, ěź’ql, ’Ţ–{•qŽ÷, •ĐŽR •×
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“ú–{ˆâ“`Šw‰ď‘ć86‰ń‘ĺ‰ď (’ˇ•lƒoƒCƒI‘ĺŠw 2014”N‚XŒŽ17“ú`19“ú)

‰Áś˜aŽő, “ĄŒő˜a”V, •ĐŽR •×
•ĄťŠJŽn‚𑣐i‚ˇ‚éDNAˆöŽqDARS2‚đ§Œä‚ˇ‚éV‹KˆöŽq‚Ě’Tő
“ú–{ˆâ“`Šw‰ď‘ć86‰ń‘ĺ‰ď (’ˇ•lƒoƒCƒI‘ĺŠw 2014”N‚XŒŽ17“ú`19“ú)

–ěŒű‘דż, čŽR—F—˘, •ĐŽR •×
ˆŮŽí—Z‡Œ^DnaA‚É‚ć‚é•ĄťŠJŽn•Ą‡‘Ě’†‚ĚDnaA•ŞŽq‚Ě”zŒüŤ‰đÍ
“ú–{ˆâ“`Šw‰ď‘ć86‰ń‘ĺ‰ď (’ˇ•lƒoƒCƒI‘ĺŠw 2014”N‚XŒŽ17“ú`19“ú)@ƒxƒXƒgƒy[ƒp[Ü

‰Áś˜aŽő, “ĄŒő˜a”V, •ĐŽR •×
‘ĺ’°‹Ű‚Ě•ĄťŠJŽn‚𑣐i‚ˇ‚é DNA ˆöŽq DARS2 ‚̉đÍ; Šj—l‘Ě’`”’Žż‚Ć‚ĚŒ‹‡‚đ‰î‚ľ‚˝×–EŽüŠú‚Ć‘B‘Š‚ɉž‚ś‚˝§Œä
‘ć 26 ‰ń ”÷ś•¨ƒVƒ“ƒ|ƒWƒEƒ€F”÷ś•¨‰ČŠw‚Ćˆă—Ă‚ĚƒVƒ“ƒtƒHƒj[ (“Œ‹ž(“sŽsƒZƒ“ƒ^[ƒzƒeƒ‹j2014”N9ŒŽ19~20“ú)

´…Ť—T, •ĐŽR •×, ‚“c˛“ń
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‘ć52‰ń“ú–{ś•¨•¨—Šw‰ď (ŽD–yŽs 2014”N‚XŒŽ25~27“új

•ĐŽR •×, ÔŠÔ—E‰î, –ěŒű‘דż, ź‘şš—m, ‹{čŒb—˘‰Á, ”öčČŒá
Analysis on regulation and mechanism in DnaB helicase interaction with the initiation complex of the Escherichia coli chromosome replication
‘ć87‰ń“ú–{ś‰ťŠw‰ďƒVƒ“ƒ|ƒWƒEƒ€uNew development in exploring structures and functions of DNA helicases sustaining genome integrityviƒI[ƒKƒiƒCƒU[G•ĐŽR@•×Ałˆä‹v—Yj(‹ž“s‘Ű‰ď‹cę 2014”N10ŒŽ15~18“új

ÔŠÔ—E‰î, ”öčČŒá, ěă Lé, •ĐŽR •×
DnaA-oriC•Ą‡‘Ě‚É‚ć‚éDnaBƒwƒŠƒJ[ƒ[‚̐is‘jŠQ‚Ć‘jŠQ‰đœˆöŽq‚Ě’Tő
‘ć87‰ń“ú–{ś‰ťŠw‰ď (‹ž“s‘Ű‰ď‹cę 2014”N10ŒŽ15~18“új

Tsutomu Katayama, Ozaki Shogo, Kenji Keyamura, Yasunori Noguchi, Saki Taniguchi, Komomo Nagata, Yukari Sakiyama, Hironori Kawakami, and Kazutoshi Kasho
The E. coli dynamin-like protein CrfC binds the replicase clamp and sustains colocalization of sister replication forks
The 9th 3R SymposiumiDNA•ĄťE‘gŠˇ‚ŚEC•œ‚̍‘ŰŠw‰ďj(Œä“aęŽs 2014”N11ŒŽ17~21“új

Kazutoshi Kasho, Fujimitsu Kazuyuki, and Tsutomu Katayama
Regulation for timely activation of the E. coli replication initiator DnaA by a specific DNA element DARS2
The 9th 3R SymposiumiDNA•ĄťE‘gŠˇ‚ŚEC•œ‚̍‘ŰŠw‰ďj(Œä“aęŽs 2014”N11ŒŽ17~21“új

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•ĐŽR •×, –ěŒű‘דż, čŽR—F—˘, ÔŠÔ—E‰î, “ĄŒő˜a”V, ‰Áś˜aŽő, ěăLé
‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťŠJŽn•Ą‡‘Ě‚đŒ`Ź‚ˇ‚éDnaA’`”’Žż‚Ě‘˝—Ę‘Ě\‘˘‚Ć“Ž‘Ԃ̉đÍ
‘ć‚R‚V‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď@ƒ[ƒNƒVƒ‡ƒbƒvuś–˝Šˆ“Ž‚đŽx‚Ś‚鍂ŽŸ•Ą‡‘Ě‚Ě“Ž‘Ô‚Ć‹@”\v (ƒpƒVƒtƒBƒR‰Ą•l 2014”N11ŒŽ25`27“ú)

2013”N
‘ŕ
Skarstad, K. and Katayama, T. (2013)
Regulating DNA Replication in Bacteria
In "DNA Replication", Edited by Bell, S.D., Me'chali, M, and DePamphilis, M.L., Cold Spring Harbor Laboratory Press
Œ´’˜˜_•ś
Kasho K., and Katayama,T. (2013)
DnaA-binding locus datA promotes DnaA-ATP hydrolysis to enable cell cycle-coordinated replication initiation
Proc. Natl. Acad. Sci. USA 110, 936-941
doi: 10.1073/pnas.1212070110
F1000Prime„‘E˜_•ś

Ozaki, S., Matsuda, Y. (equal contributors), Keyamura, K., Kawakami, H., Noguchi, Y., Kasho, K., Nagata, K., Masuda, T., Sakiyama, Y., and Katayama, T. (2013)
A replicase clamp-binding dynamin-like protein promotes colocalization of the nascent DNA strands and equipartitioning of chromosomes in E. coli
Cell Reports 4(5):985-995
(http://dx.doi.org/10.1016/j.celrep.2013.07.040)
“ŕ—eĐ‰îƒy[ƒW

Su'etsugu, M., Harada, Y., Keyamura, K.(equal contributors), Matsunaga, C., Kasho. K., Abe,Y., Ueda, T., and Katayama,T. (2013)
The DnaA N-terminal domain interacts with Hda to facilitate replicase clamp-mediated inactivation of DnaA
Environ. Microbiol. 15(12):3183-3195
doi: 10.1111/1462-2920.12147

Fujiwara, K., Katayama,T., and Nomura, M. S. (2013)
Cooperative working of bacterial chromosome replication proteins generated by a reconstituted protein expression system
Nucleic Acids Res. 41(14):7176-7183.
doi: 10.1093/nar/gkt489.

Aramaki, T., Abe,Y. (equal contributors), Ohkuri, T., Mishima T., Yamashita, S., Katayama, T., and Ueda, T. (2013)
Domain separation and chracterization of PriC, a replication restart primosome factor in Escherichia coli
Genes Cells 18(9):723-732.
doi: 10.1111/gtc.12069.

Aramaki, T., Abe,Y. (equal contributors), Katayama, T., and Ueda, T. (2013)
Solution structure of the N-terminal domain of a replication restart primosome factor, PriC, in Escherichia coli
Protein Sci. 22(9):1279-1286
doi: 10.1002/pro.2314.

Žĺ—vŠw‰ď”­•\
ěă LéA•ĐŽR •×ABruce Stillman
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Katayama, T., Kasho, K., Noguchi, Y., Sakiyama, Y., Matoba, T., Tanaka, H., Taniguchi, M., Ozaki, O., Fujimitsu, K., and Kawakami, H.
DnaA assemblies on the replication origin oriC, DARS and the datA locus for the replication initiation and regulation of the initiation in E. coli
‘ć86‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď International Session: Assembly and architecture of protein complexes regulating inheritance and stable maintenance of genome (organizers: Hisao Masai, Tsutomu Katayama) i2013”N9ŒŽ11|13“ú@‰Ą•lj

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2012”N
‘ŕ
Su'etsugu. M., and Katayama, T. (2012)
Chromosome replication in E. coli and B. subtilis.
In "Escherichia coli and Bacillus subtilis; The Frontiers of Molecular Microbiology Revisited", Edited by Yoshito Sadaie and Kouji Matsumoto, Research Signpost
http://www.trnres.com/ebookcontents.php?id=139
Œ´’˜˜_•ś
Ozaki, S., and Katayama, T. (2012)
Highly organized DnaA-oriC complexes recruit the single-stranded DNA for replication initiation
Nucleic Acids Res. 40(4), 1648-1665 (doi: 10.1093/nar/gkr832)

Ozaki, S., Noguchi, Y., Hayashi, Y., Miyazaki, E., and Katayama, T. (2012)
Differentiation of the DnaA-oriC sub-complex for DNA unwinding in a replication initiation complex
J. Biol. Chem. 287(44), 37458-37471@(doi: 10.1074/jbc.M112.371052)

Ozaki, S., Noguchi, Y., Nishimura, M., and Katayama, T. (2012)
Stable nucleotide binding to DnaA requires a specific glutamic acid residue within the AAA+ box II motif
J. Struct. Biol. 179, 242-250 (doi: 10.1016/j.jsb2012.05.001)

Žĺ—vŠw‰ď”­•\
Ozaki,S., Noguchi, Y., Miyazaki, E., and Katayama, T.
Reconstitution and molecular anayomy of oriC initiation complexes in E. coli chromosomal replication: ssDNA rescruitmentand roles for IHF and dictinct DnaA oligomers formed on oriC.
EMBO Workshop: Reconstructing the essential bacterial cell cycle machinery (Segovia, Spain, September 16-19, 2012)

Katayama,T.
A novel model for overall structure of a replication initiation complex and duplex unwinding mechanism in E. coli
The 8th 3R Symposium together with National Institute of Genetics 2012 International Symposium: Molecular mechanism and pathology of the 3R (Awaji, Japan, November 25-28, 2012)

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Finding and moleclular analysis of a novel inactivation mechanism forn the replication initiator DnaA by a specific chromosomal locus.
‘ć35‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď ƒ[ƒNƒVƒ‡ƒbƒvuChromosome replication and its coordination with nucleo-cellular functionsv(ƒI[ƒKƒiƒCƒU[F“c’†˝ŽiA™–{‚Ě‚ź‚݁ji•Ÿ‰ŞA2012”N12ŒŽ11-14“új

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DnaA§ŒäƒTƒCƒNƒ‹‚̍č\’z‚É‚ć‚é‰đ–žFV‚˝‚ČDnaA-ATP‰Á…•Ş‰đŒo˜H‚ĆŠj—l‘̍\’zˆöŽq‚Ě–đŠ„
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iŽQlj
ěăLéABruce Stillman (CSHL)
o‰čy•ępre-RCŒ`Ź‚̐¸ť‘gŠˇ‚Ś’`”’Žż‚đ—p‚˘‚˝ŽŽŒąŠÇ“ŕÄ\Ź‚Ćpre-IC\ŹˆöŽq‚ĚƒŠƒNƒ‹[ƒgƒƒ“ƒg
“ú–{ˆâ“`Šw‰ď‘ć84‰ń‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvuŒ´Šjś•¨‚ɏK‚¤ˆâ“`î•ńˆŔ’萍‚ĚˆŰŽ‹@\‚ĚŒ´—v(˘˜blF•ĐŽR@•×AÎ–ě—Ǐƒji•Ÿ‰ŞA2012”N‚XŒŽ24-26“új

2011”N
‘ŕ
•ĐŽR@•×i2011j
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29ŠŞ7†i‘Š§jA83-89•Ĺ
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Keyamura, K., and Katayama, T. (2011)
The DnaA DNA-binding domain binds to Hda to promote the inter-AAA+ domain interaction involved in the regulatory inactivation of DnaA
J. Biol. Chem. 286(33), 29336-29436

Charbon, G., Riber, L., Cohen, M., Skovgaard, O., Fujimitsu, K., Katayama, T., Lżbner-Olesen, A. (2011)
Suppressors of DnaA-ATP imposed overinitiation in Escherichia coli
Mol. Microbiol. 79(4), 914-928

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Ozaki, S. and Katayama, T.
Architecture and mechanism for DNA unwinding of the ATP-DnaA initiation complex of the E. coli chromosomal replication
9th International Conference on AAA Proteins (Kumamoto, November 6-10, 2011) iľ‘ŇŒű‰‰j

Keyamura, K. and Katayama, T.
The Interaction Mode between DnaA and Hda AAA+ Proteins in Regulatory Inactivation of DnaA, 9th International Conference on AAA Proteins (Kumamoto, November 6-10, 2011)@iƒ|ƒXƒ^[”­•\j

Kasho, K., Fujimitsu, K. and Katayama, T.
Search and analysis for novel stimulators of DARS2, DnaA-reactivating sequence 2
9th International Conference on AAA Proteins (Kumamoto , November 6-10, 2011)iƒ|ƒXƒ^[”­•\j

Noguchi, Y., Ozaki, S. and Katayama, T.
Role for a residue within AAA+ domain of DnaA protein in stable maintenance of bound nucleotide
9th International Conference on AAA Proteins (Kumamoto , November 6-10, 2011)iƒ|ƒXƒ^[”­•\j

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Šj—l‘Ě‹ĂW’`”’Žż‚É‚ć‚é•ĄťŠJŽn‘ŁiˆöŽqDARS2 (DnaA-reactivating sequence 2) ‚Ě‘B‘ŠA‹y‚Ń×–EŽüŠú‚ɉž‚ś‚˝§Œä‹@\
“ú–{ˆâ“`Šw‰ď‘ć83‰ń‘ĺ‰ďA‹ž“s‘ĺŠwA2011”N9ŒŽ20-23“ú@Best PapersÜ

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“ú–{ˆâ“`Šw‰ď‘ć83‰ń‘ĺ‰ďA‹ž“s‘ĺŠwA2011”N9ŒŽ20-23“ú

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–ěŒű‘דżA“ĄŒő˜a”VA–Ń’J‘şŒŤŽiA•ĐŽR@•×
‘˝ƒRƒs[‰ť‚É‚ć‚č‘ĺ’°‹Ű‚̐őF‘Ě•ĄťŠJŽn‚Ě“Ż’˛Ť‚ɉe‹ż‚đ—^‚Ś‚éˆâ“`Žq‚Ě“ÁŤ
‘ć21‰ńDNA•ĄťE‘gŠˇ‚ŚEƒQƒmƒ€ˆŔ’萍§Œäƒ[ƒNƒVƒ‡ƒbƒv (•Ÿ‰ŞŒ§•Ÿ’ĂŽsA2011”N10ŒŽ25`27“úA˘˜blF’Ţ–{•qŽ÷E•ĐŽR@•×E“Ą“c‰ër)

Ozaki, S. and Katayama, T.
Dynamics in DNA unwinding of the DnaA-/oriC/complex
‘ć34‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďƒVƒ“ƒ|ƒWƒEƒ€"Frontier of reconstitution biology toward understanding of principals in dynamics of high-order complexes "(Organizers: Tsutomu Katayama (Kyushu Univ.), Hiroshi Iwasaki (Tokyo Inst. Of Tech.))
‰Ą•l‘Ű‰ď‹cęA2011”N12ŒŽ13-16“ú

2010”N
‘ŕ
Katayama, T., Ozaki, S., Keyamura, K. and Fujimitsu, K. (2010)
Regulation of the replication cycle: Conserved and diverse regulatory systems for DnaA and oriC
Nature Rev. Microbiol. 8(3):163-170

Kawakami, H. and Katayama, T. (2010)
DnaA, ORC, and Cdc6: Similarity beyond the domains of life and diversity
Biochem. Cell Biol. 88(22): 49-62

Œ´’˜˜_•ś
Nakamura, K. and Katayama, T. (2010)
Novel essential residues of Hda for interaction with DnaA in the regulatory inactivation of DnaA: Unique roles for Hda AAA+ Box VI and VII motifs
Mol. Microbiol. 76(2): 302-317
Žĺ—vŠw‰ď”­•\
Fujimitsu, K., Kasho, K., Ozaki, S., Senriuchi, T. and Katayama, T.
DARS, DnaA-reactivating sequence promotes exchange of DnaA-bound ADP to ATP
EMBO Conference Series; Replication /Repair • Segregation of Chromosomes, Freiburg-Munzingen, Germany, June 13-17, 2010@(Oral presentation)

Ozaki, S. and Katayama, T. (2010)
Mechanism for ATP-DnaA-dependent unwinding of duplex DNA within the chromosomal replication origin
EMBO Conference Series; Replication /Repair • Segregation of Chromosomes , Freiburg-Munzingen, Germany, June 13-17, 2010 (Poster presentation)

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‘ĺ’°‹Ű‚ĚƒCƒjƒVƒG[ƒ^[DnaA‚đ‰î‚ľ‚˝•ĄťŠJŽn§Œä‹@\‚̉đÍ
2009”N“x ‘—§ˆâ“`ŠwŒ¤‹†Š‹¤“ŻŒ¤‹†‰ďuƒQƒmƒ€î•ń‚đŠˆ—p‚ľ‚˝’P×–E×–E@‘BƒVƒXƒeƒ€‚ĚŒ¤‹†vAŽO“‡A2010”N3ŒŽ30“ú- 31“ú

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uőF‘ĚƒTƒCƒNƒ‹v“Á’č—Ěˆć‰ď‹cĹI‰ńA–ś“‡A2010”N3ŒŽ1-3“ú

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‘ĺ’°‹ŰőF‘Ě•ĄťŠJŽn‚đ§Œä‚ˇ‚éDnaA-oriC•Ą‡‘Ě‚Ě‹@”\\‘˘
‘ć7‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď Aˆ˘‘hA2010”N6ŒŽ3-4“ú

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DiaA‚É‚ć‚éDnaB‘•’…§Œä‹@\‚̉đ–ž
‘ć7‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď Aˆ˘‘hA2010”N6ŒŽ3-4“ú

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‰Áś˜aŽőA“ĄŒő˜a”VA”öčČŒáA–Ń’J‘şŒŤŽiA•ĐŽR@•×
ƒqƒXƒgƒ“—l’`”’Žż‚É‚ć‚é•ĄťŠJŽn‘ŁiˆöŽqDARS2 (DnaA-reactivating sequence 2)‚̐§Œä—lŽŽ‚̉đ–ž
“ú–{ˆâ“`Šw‰ď‘ć82‰ń‘ĺ‰ďAŽD–yA2010”N9ŒŽ20-23“ú

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2009”N
‘ŕ
Ozaki, S., and Katayama, T. (2009)
DnaA structure, function, and dynamics in the initiation at the chromosomal origin
Plasmid 62: 71- 82

•ĐŽR@•×i2009j
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54ŠŞ4†A343-349•Ĺ

Œ´’˜˜_•ś
Fujimitsu, K., Senriuchi, T., and Katayama, T. (2009)
Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA
Genes Dev. 23(10): 1221-1233
F1000Prime„‘E˜_•ś

Keyamura, K., Abe, Y., Higashi, M., Ueda, T., and Katayama, T. (2009)
DiaA dynamics are coupled with changes in initial origin complexes leading to helicase loading
J. Biol. Chem. 284(37): 25038-25050

Riber, L., Fujimitsu, K., Katayama, T., and Lżbner-Olesen, A. (2009)
Loss of Hda activity stimulates replication initiation from I-box, but not R4 mutant origins in Escherichia coli
Mol. Microbiol. 71(1):107-22

Žĺ—vŠw‰ď”­•\
Fujimitsu, K., Senriuchi, T., and Katayama, T. (2009)
The replication initiator DnaA is reactivated in a specific nucleoprotein complex
8th International Conference on AAA Proteins, Tronto, Canada, July 12-16 (ľ‘ŇŒű‰‰)

Nakamura, K. and Katayama, T (2009)
AAA+ domain-specific interaction of Hda with DnaA in the replicase clamp-mediated DnaA-ATP hydrolysis
8th International Conference on AAA Proteins, Tronto, Canada, July 12-16 ‰@śƒ|ƒXƒhƒN—DGƒ|ƒXƒ^[Ü

Katayama, T. (2009)
Functional mechanism and regulation for the E. coli chromosomal replication initiator DnaA
12th Asia-Pacific International Molecular Biology Network Conference, Penang, Malaysia, October 27-28 Arthur Kornberg Memorial Lecture Award

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DARSF‘ĺ’°‹ŰDnaA‚đŠˆŤ‰ť‚ˇ‚éV‹KőF‘ĚDNAˆöŽq
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–Ń’J‘şŒŤŽiA“Œ@‰ë—TA•ĐŽR@•×
‘ĺ’°‹Ű‚Ě•ĄťŠJŽn•Ą‡‘ĚŒ`Ź‚É‚¨‚Ż‚éDiaA-DnaA‘ŠŒÝě—pƒƒJƒjƒYƒ€‚̉đÍ
“ú–{ˆâ“`Šw‰ď‘ć81‰ń‘ĺ‰ďAMB‘ĺŠwA2009”N9ŒŽ16-18“ú Best PaperÜ

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’†‘şŒŤ‘žA––ŽŸłKA•ĐŽR@•×
ATPŒ‹‡Œ^DnaA‚Ć•ĄťƒNƒ‰ƒ“ƒv‚É‚ć‚éDnaA•sŠˆŤ‰ťˆöŽqHda‚ĚŠˆŤ§Œä
‘ć82‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ďuƒQƒmƒ€‚Ćˆâ“`î•ńvŒű“Ş”­•\A_ŒËA10ŒŽ21-24“ú, 2009”N

Kazuyuki Fujimitsu, Kazutoshi Kasho, Takayuki Senriuchi, Hiroki Ohyama,
and Tsutomu Katayama
DARS: the chromosomal locus for reactivation of the replication initiator DnaA in E. coli
International Symposium on Chromosomal Cycle and Genome Dynamics, Nasu, Tochigi, Japan, November 10-12, 2009

Tsutomu Katayama, Kenji Keyamura, Kazuyuki Fujimitsu, Shogo Ozaki, Saori Shinozuka, Toshiyuki Hatano and Hironori Niki
Novel fundamental mechanism regulating the replicational initiation in E. coli
‘ć32‰ń“ú–{•ŞŽqś•¨Šw‰ďƒ[ƒNƒVƒ‡ƒbƒvuFrontier of Bacterial Cell DuplicationiŒ´Šjś•¨‚ĹŒŠ‚˘‚ž‚ł‚ę‚˝×–E•Ąť‚ĚŠî–{•ŞŽq‹@\jvA‰Ą•lA2009”N12ŒŽ9-12“ú

•ĐŽR@•×A“ĄŒő˜a”VA–Ń’J‘şŒŤŽiA”öčČŒáA‰Áś˜aŽőA“Œ@‰ë—T
‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťŠJŽn‚đ§Œä‚ˇ‚éV‚˝‚ČŠî–{•ŞŽq‹@\
‘ć‚P‰ńP&P‡“ŻŒöŠJƒVƒ“ƒ|ƒWƒEƒ€uś–˝Šˆ“Ž‚đ§Œä‚ˇ‚鍂ŽŸ•Ą‡‘Ě‚Ě\‘˘‚Ć‹@”\v
ŽĺĂF‹ăB‘ĺŠwP&Pu‹ăBŒ—\‘˘ś•¨ŠwŒ¤‹†‹’“_Œ`Ź‚đ–ÚŽw‚ľ‚˝‹ăB‘ĺŠw‚É‚¨‚Ż‚錤‹†E‹łˆçƒRƒ“ƒ\[ƒVƒAƒ€Œ`Źvi\‘˘ś•¨Šw‹’“_Œ`Źj‚¨‚ć‚сu’´‚ŽŸ•Ą‡‘̉đÍ‚ÉŠî‚Ă‚­ƒQƒmƒ€“Ž‘ÔŒ¤‹†ƒvƒƒWƒFƒNƒgvi’´‚ŽŸ•Ą‡‘̉đÍj
•Ÿ‰ŞŽsA‹ăB‘ĺŠwˆăŠw•”•S”Nu“°A2009”N12ŒŽ22-23“ú

2008”N
‘ŕ
Katayama. T. (2008)
Roles for the AAA+ motifs of DnaA in the initiation of DNA replication
Biochem. Soc. Trans. 36(1), 78-82

•ĐŽR@•×i2008j
ƒCƒjƒVƒG[ƒ^[DnaAƒ^ƒ“ƒpƒNŽż‚É‚ć‚é‘ĺ’°‹ŰőF‘Ě•ĄťŠJŽn‹@\
×–EHŠwi10ŒŽ†jGŽĐ, 27ŠŞ10†, 974-979•Ĺ

Œ´’˜˜_•ś
Ozaki, S., Kawakami,H., Nakamura, K., Fujikawa, N., Kagawa, W., Park, S.-Y., Yokoyama, S., Kurumizaka, H., and Katayama, T. (2008)
A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin
J. Biol. Chem. 283(13), 8351-8362

Fujimitsu, K., Su'etsugu, M., Yamaguchi, Y. (equal contributors), Mazda, K., Fu, N., Kawakami, H., and Katayama, T. (2008)
Modes of over-initiation, dnaA gene expression and the inhibition of cell division in a novel cold-sensitive hda mutant in Escherichia coli
J. Bacteriol. 190 (15), 5368-5381

Su'etsugu, M., Nakamura, K., Keyamura, K., Kudo, Y., and Katayama, T. (2008)
Hda monomerization by ADP binding promotes replicase clamp-mediated DnaA-ATP hydrolysis
J. Biol. Chem. 283 (54), 36118-36131

Žĺ—vŠw‰ď”­•\
Keyamura, K.*, Fujikawa, N., Ishida, T., Ozaki, S., Su'etsugu, M., Fujimitsu, K., Kagawa, W., Yokoyama, S., Kurumizaka, H., and Katayama, T.
A novel initiation-stimulator DiaA directly promotes ATP-DnaA-specific initiation complexes in E. coli
Keysone Symposia in Molecular and Cellular Biology: DNA Replication and Recombination, Santa Fe, NM, USA, Feb 10-15, 2008 (Œű“Ş”­•\) *Keystone Schoolarship Winner

Katayama, T., Ozaki, S., Keyamura, K., Kawakami, H., Fujikawa, N., Kagawa, W., Nakamura, K., Fujimitsu, K., Su'etsugu, M., Yokoyama, S., and Kurumizaka, H.
Analysis on Mechanisms of ATP-DnaA Assembly on oriC and Duplex Unwinding
EMBO Workshop on Replication & Segregation of Chromosomes, Geilo, Norway, June 16-20, 2008 (ľ‘ŇŒű‰‰j

•ĐŽR@•×C–Ń’J‘şŒŤŽiC”öčČŒáC“Ąě”T‚č‰fCě@˜jCěăLéC’†‘şŒŤ‘žCÎ“c‘ô–C––ŽŸłKC“ĄŒő˜a”VC‰ĄŽR–ΔVCŒÓ“âmŽu
V‹KˆöŽqDiaA ’`”’Žż‚đŠÜ‚ށC•ĄťŠJŽn•Ą‡‘Ě‚Ě\‘˘‚ĆƒƒJƒjƒYƒ€
‘ć‚W‰ń’`”’Žż‰ČŠw‰ď”N‰ď ƒ[ƒNƒVƒ‡ƒbƒvu\‘˘‚Š‚痝‰đ‚ˇ‚éDNAŒ‹‡ƒ^ƒ“ƒpƒNŽż‚Ě‹@”\v, “Œ‹ž“s]ŒËě‹ć, 6ŒŽ10-12“ú, 2008”Niľ‘ŇŒű‰‰j

”öčČŒá, •ĐŽR@•×
DnaA‚É‚ć‚é2d˝ŠJ—ô‚É‚¨‚Ż‚é•Ąť‹N“_‚̍ŏŹ‹@”\\‘˘
‘ć80‰ń“ú–{ˆâ“`Šw‰ď‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvuőF‘Ě‹@”\‚ĆDNAƒgƒ‰ƒ“ƒXƒAƒNƒVƒ‡ƒ“v, –źŒĂ‰Ž‘ĺŠw, 9ŒŽ3`‚T“ú, 2008”N
Best PaperÜ ƒŠƒ“ƒNFŠw‰ďŽŠÖ˜A‹LŽ–

Katayama, T.
Mechanisms of ATP-DnaA Assembly and Duplex DNA Unwinding for the Initiation of DNA Replication in Reconstituted Systems
The 17th RIKEN CDB Meeting "Towards Synthesis of Cells", Kobe, Japan, October 14-15, 2008iľ‘ŇŒű‰‰j

Katayama, T.
Mechanism and Regulation for ATP-DnaA Assembly and Duplex DNA Unwinding on the E. coli Chromosomal Origin oriC
6th 3R (Replication, Recombination, Repair) Symposium, Kakegawa, Japan, October 27-30, 2008 (ľ‘ŇŒű‰‰)

Su'etsugu, M., Nakamura, K., Keyamura, K., and Katayama, T.
Functional regulation of Hda, a replicase clamp-binding protein that promotes the regulatory inactivation of DnaA in E. coli
‘ć31‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ď/‘ć81‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď‡“Ż‘ĺ‰ďƒVƒ“ƒ|ƒWƒEƒ€uőF‘ĚƒTƒCƒNƒ‹‚̐§Œä‹@\viƒI[ƒKƒiƒCƒU[Fłˆä‹v—YA‘ž“c–MŽjj, _ŒËA12ŒŽ9`12“úA2008”N

2007”N
‘ŕ
•ĐŽR@•×i2007j
•ĄťÄŠJŽn—}§‚Ě•ŞŽq‹@\
ŽŔŒąˆăŠwA25ŠŞ‚T†i‘Š§uőF‘ĚƒTƒCƒNƒ‹vjA49-55•ĹA—r“yŽĐ
Œ´’˜˜_•ś
Keyamura, K., Fujikawa, N, (equal contributors), Ishida, T., Ozaki, S., Su'etsugu, M., Fujimitsu, K., Kagawa, W., Yokoyama, S., Kurumizaka, H.* and Katayama, T.* (*Co-corresponding authos) (2007)
The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP-DnaA-specific initiation complexes
Genes Dev. 21, 2083-2099

Abe, Y., Jo, T., Matsuda, Y., Matsunaga, C., Katayama, T.*, and Ueda, T.* (*Co-corresponding authors) (2007)
Structure and function of DnaA N-terminal domains: Specific sites and mechanisms in inter-DnaA interaction and in DnaB helicase loading on oriC
J. Biol. Chem. 282(24),17816-17827 JBC Paper of the Week

Abe, Y., Watanabe, N., Yoshida, Y., Ebata, F., Katayama, T., and Ueda, T. (2007)
Assignment of 1H, 13C and 15N resonances of N-terminal domains of DnaA protein
Biomol. NMR Assign. 1, 57-59

Žĺ—vŠw‰ď”­•\
Katayama, T., Ozaki, S., Kawakami, H., Nakamura, N., Keyamura, K., Fujikawa, N., Kagawa, W., Yokoyama, S. and Kurumizaka, H.
Biochemical analysis of DnaA AAA+ domain on the ATP-dependent regulation for the initiation of chromosomal replication.
7th International Meeting on AAA Proteins, Royal Agricultural College, Cirencester, UK, Sept 9-13, 2007 (ľ‘ҍu‰‰j

Ozaki, S., Kawakami, H., Nakamura, N., Fujikawa, N., Kagawa, W., Yokoyama, S., Kurumizaka, H.and Katayama, T.
Role for specific residues of DnaA AAA+ domain in duplex DNA unwinding during the initiation of chromosomal replication.
7th International Meeting on AAA Proteins, Royal Agricultural College, Cirencester, UK, Sept 9-13, 2007

ź“c—YěA•ĐŽR@•×
V‹KƒNƒ‰ƒ“ƒvŒ‹‡ˆöŽqRisA‚Ě‹@”\‰đÍ
‘ć4‰ń 21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď, “ĄŽ}Žs, 7ŒŽ17`17“ú

“ĄŒő˜a”VAç—˘“ŕŒ[sA•ĐŽR@•×
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‘ć4‰ń 21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ď, “ĄŽ}Žs, 7ŒŽ17`17“ú

––ŽŸłKA“ĄŒő˜a”VA•ĐŽR •×
×–EŽüŠúis‚Ć‹¤–đ‚ľ‚˝‘ĺ’°‹Ű•ĄťŠJŽn’`”’ŽżDnaA‚ĚŠˆŤ§Œä‹@\
“Á’č—ĚˆćwƒoƒCƒI‘€ěxŽáŽčŒ¤‹†ŽŇ‘ć‚Q‰ńƒ[ƒNƒVƒ‡ƒbƒvA“Œ‹ž“sŹ‹ŕˆäŽsA7ŒŽ20“ú

–Ń’J‘şŒŤŽiAÎ“c‘ô–A”öčČŒáA––ŽŸłKA“ĄŒő˜a”VA•ĐŽR@•×
‘ĺ’°‹Ű‚̐őF‘Ě•ĄťŠJŽn”˝‰ž‚Ě“KŽž“IŠˆŤ‰ť‚đ§Œä‚ˇ‚é•ŞŽq‹@\
‘ć19‰ń”÷ś•¨ƒVƒ“ƒ|ƒWƒEƒ€u”÷ś•¨‰ČŠw‚Ě”­“W‚ĆŠ´őÇ‘΍ôv, “Œ‹ž‘ĺŠw, 9ŒŽ7“ú`8“ú

•ĐŽR@•×A–Ń’J‘şŒŤŽiA“Ąě”T‚č‰fAÎ“c‘ô–A”öčČŒáA––ŽŸłKA“ĄŒő˜a”VAě@˜jA‰ĄŽR–ΔVAŒÓ“âmŽu
DnaAŒ‹‡ˆöŽqDiaA’`”’Žż‚É‚ć‚é•ĄťŠJŽn‚̐§Œä‹@\
“ú–{ˆâ“`Šw‰ď‘ć79‰ń‘ĺ‰ď, ƒ~ƒjƒVƒ“ƒ|ƒWƒEƒ€uőF‘Ě‚Ě•Ąť‹@\‚ĆƒQƒmƒ€ˆŔ’萍v, ‰ŞŽR‘ĺŠw,9ŒŽ19`21“ú

”öčČŒáAěăLéA’†‘şŒŤ‘žA“Ąě”T‚č‰fAě@˜jA‰ĄŽR–ΔVAŒÓ“âmŽuA•ĐŽR@•×
őF‘Ě•ĄťŠJŽn“_‚Ě2d˝DNAŠJ—ô‚đ§Œä‚ˇ‚éDnaA VŠď‹@”\\‘˘‚̉đÍ
“ú–{ˆâ“`Šw‰ď‘ć79‰ń‘ĺ‰ď, ‰ŞŽR‘ĺŠw, 9ŒŽ19`21“ú, Best PaperÜ

•ĐŽR@•×A”öčČŒáAěăLéA’†‘şŒŤ‘žA“Ąě”T‚č‰fAě@˜jA‰ĄŽR–ΔVAŒÓ“âmŽu
DnaA‚É‚ć‚é•ĄťŠJŽn•Ą‡‘Ě‚ĚŒ`Ź‚Ć2d˝ŠJ—ô‹@\ƒ‚ƒfƒ‹
‘ć30‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďE‘ć80‰ń“ú–{ś‰ťŠw‰ď‘ĺ‰ď‡“Ż‘ĺ‰ď ƒ[ƒNƒVƒ‡ƒbƒvu•ĄťŠJŽn•Ą‡‘ĚŒ`Ź‚Ěƒ_ƒCƒiƒ~ƒNƒX‚Ć•ŞŽq§ŒäviƒI[ƒKƒiƒCƒU[F•ĐŽR@•×Aź’JG’jj, ‰Ą•l, 12ŒŽ11`15“ú

2006”N
’˜‘
–Ń’J‘şŒŤŽiA”öčČŒáA•ĐŽR@•× (2006)
‘ĺ’°‹ŰDnaA’`”’Žż‚̐¸ť–@
uƒ^ƒ“ƒpƒNŽżŽŔŒąƒ}ƒjƒ…ƒAƒ‹viŒÓ“âmŽu•ŇjA7-14•ĹA’Š‘q‘“X
Œ´’˜˜_•ś
Kawakami, H., Ozaki, S. (equal contributors), Suzuki, S., Nakamura, K., Senriuchi, T., Su'etsugu, M., Fujimitsu, K., and Katayama, T. (2006)
The exceptionally tight affinity of DnaA for ATP/ADP requires a unique aspartic acid residue in the AAA+ sensor 1 motif
Mol. Microbiol. 62(5), 1310-1324

Ozaki, S., Fujimitsu, K., Kurumizaka, H., and Katayama, T. (2006)
The DnaA homolog of the hyperthermophilic eubacterium Thermotoga maritima forms an open complex with a minimal 149-bp origin region in an ATP-dependent manner
Genes Cells 11, 425-438

Kawakami, H., Su'etsugu, M. and Katayama, T. (2006)
An isolated Hda-clamp complex is functional in the regulatory inactivation of DnaA and DNA replication
J. Struct. Biol. 156, 220-229

Ote, T., Hashimoto, M., Ikeuchi, Y., Su'etsugu, M., Suzuki, T., Katayama, T., and Kato, J. (2006)
Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation
Mol. Microbiol. 59(1), 265-274

Žĺ—vŠw‰ď”­•\
Katayama, T., Ozaki, S., Kawakami, H., and Kurumizaka, H.
Mechanism in the ATP-specific Conformational Activation of the Initiation Complex by DnaA initiator
The First International Symposium on the MEXT Priority Research Project:The Chromosome Cycle (A Satellite Meeting of 20th IUBMB International Congress of Biochemistry and Molecular Biology & 11th FAOBMB Congress), June 26-27, 2006, Sanjo Conference Hall (Tokyo University Hongo Campus) iŒű“Ş”­•\j

Katayama, T., Matsuda, Y., Kawakami, H., and Su'etsugu, M.
Analysis on molecular mechanism of the clamp/Hda-dependent DnaA-ATP hydrolysis and on a novel role for the clamp
EMBO Workshop: Cell Cycle and Cytoskeletal Elements in Bacteria, Copenhagen, Denmark, Aug 23-27, 2006

Su'etsugu, M., Keyamura, K., Kudo, Y., Nakamura, K., and Katayama, T.
The nucleotide-dependent activation of Hda in the replicase clamp-mediated DnaA-ATP hydrolysis in Escherichia coli
EMBO Workshop: Cell Cycle and Cytoskeletal Elements in Bacteria, Copenhagen, Denmark, Aug 23-27, 2006

–Ń’J‘şŒŤŽiA––ŽŸłKAÎ“c‘ô–AA“c@łA•ĐŽR@•×
‘ĺ’°‹Ű‚̐őF‘Ě•ĄťŠJŽnˆöŽqDnaA‚đ•sŠˆŤ‰ť‚ˇ‚é•ŞŽq‹@\FDnaA‚ĚDNAŒ‹‡ƒhƒƒCƒ“‚Ě•ĎˆŮ‘Ě‰đÍ
‘ć‚R‰ń21˘‹I‘ĺ’°‹ŰŒ¤‹†‰ďFƒ‚ƒfƒ‹ś•¨‘ĺ’°‹Ű‚Ě“‡“I—‰đ‚đ‚ß‚´‚ľ‚āAŽ ‰ęA10ŒŽ3`‚S“úiŒű“Ş”­•\Ap21j

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‘ć18‰ńDNA•Ąťƒ[ƒNƒVƒ‡ƒbƒvA”MŠCA10ŒŽ30“ú`11ŒŽ1“úiŒű“Ş”­•\Ap3j

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‘ĺ’°‹ŰƒXƒ‰ƒCƒfƒBƒ“ƒOƒNƒ‰ƒ“ƒvV‹K‘ŠŒÝě—pˆöŽq‚Ě“Ż’č‚Ć‚ť‚Ě‹@”\‰đÍ
‘ć18‰ńDNA•Ąťƒ[ƒNƒVƒ‡ƒbƒvA”MŠCA10ŒŽ30“ú`11ŒŽ1“úiŒű“Ş”­•\Ap32j

”öčČŒáAěăLéA’†‘şŒŤ‘žAŒÓ“âmŽuA•ĐŽR@•×
DnaA’`”’Žż‚Ě“ÁˆŮ“IAAA+—Ěˆć‚đ‰î‚ľ‚˝•ĄťŠJŽn“_ŠJ—ô‚ĚƒƒJƒjƒYƒ€
“ú–{•ŞŽqś•¨Šw‰ď2006ƒtƒH[ƒ‰ƒ€AƒVƒ“ƒ|ƒWƒEƒ€uőF‘Ě•ĄťŠJŽnƒTƒCƒNƒ‹‚Ě•ŞŽq‹@\‚Ɛ§ŒäƒXƒCƒbƒ`vi˘˜blF•ĐŽR@•×Aź’JG’jjA–źŒĂ‰ŽA12ŒŽ6`8“úiŒű“Ş”­•\Ap207j

2005”N
Œ´’˜˜_•ś
Kawakami, H., Keyamura, K., and Katayama, T. (2005)
Formation of an ATP-DnaA-specific initiation complex requires DnaA arginine-285, a conserved motif in the AAA+ protein family
J. Biol. Chem. 280(29), 27420-27430

Su'etsugu, M., Shimuta, T., Ishida, T., Kawakami, H. and Katayama, T. (2005)
Protein associations in DnaA-ATP hydrolysis mediated by the Hda-replicase clamp complex
J. Biol. Chem. 280(8), 6528-6536

Hishimoto, M., Ichimura, Y., Mizoguchi, H., Tanaka, K., Fujimitsu, K., Keyamura, K., Ote, T., Yamakawa, T., Yamazaki, Y., Mori, H., Katayama, T., and Kato, J. (2005)
Cell size and nucleoid organization of engineered Escherichia coli cells with a reduced genome
Mol. Microbiol. 55(1), 137-149

Shioi, S., Ose, T., Maenaka, K., Shiroishi, M., Abe, Y., Kohda, D., Katayama, T., and Ueda, T. (2005)
Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site
Biochem. Biophys. Res. Commun. 326(4), 766-776

Žĺ—vŠw‰ď”­•\
Katayama, ‚s., Su'etsugu, M., Kawakami, H., Keyamura, K., Shimuta, T., Ishida, T., Kudo, Y., and Matsunaga, C.
Molecular mechanisms of the regulatory inactivation of DnaA: Functional and dynamic associations of DnaA, Hda, and the DNA polymerase III sliding clamp
ICGEB (International Center of Genetic Engineering and Biotechnology) Workshop on "Chromosome Duplication and Segregation", May 2-5, 2005, Trieste, Italy iŒű“Ş”­•\j

•ĐŽR@•×
ATPŒ^DnaAƒ^ƒ“ƒpƒNŽż‚É‚ć‚é•ĄťŠJŽn‚Ć‚ť‚̐§Œä‚Ě•ŞŽq‹@\
‘ĺă‘ĺŠw’`”’ŽżŒ¤‹†ŠƒZƒ~ƒi[uőF‘ĚƒTƒCƒNƒ‹‚̐§Œäƒlƒbƒgƒ[ƒNvA‘ĺăA2005”N‚SŒŽ18-19“úiľ‘ҍu‰‰j

Katayama, T., Kawakami, H., Su'etsugu, M., Ozaki, S., Kudo, Y., Keyamura, K., Shimuta, T., and Ishida, T.
Mechanisms in Regulation for Initiation of the E. coli Chromosomal Replication: Unique roles for the AAA+ Motifs of DnaA and Hda
6th International Conference on AAA Proteins, September 14-18, 2005, Schloss Seggau, Austria

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Katayama, T., Kawakami, H., Ozaki, S., and Kurumizaka, H.
Analysis on Structure and Regulation of a Bacterial Initiation Complex
‘ć28‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďAƒVƒ“ƒ|ƒWƒEƒ€u•Ąť‘•’u‚̏W‡‚ĆˆŰŽvA•Ÿ‰ŞA2005”N12ŒŽ7“ú`10“ú

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DnaAŒ‹‡ŤATP‚Ě•ĄťŠJŽn•Ą‡‘ĚŒ`Ź‚É‚¨‚Ż‚é–đŠ„
‘ć28‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďAƒ[ƒNƒVƒ‡ƒbƒvu×–E‹@”\‚ĚƒL[ƒvƒŒƒCƒ„[AAA+ƒ^ƒ“ƒpƒNŽż‚̐˘ŠEvA•Ÿ‰ŞA2005”N12ŒŽ7“ú`10“ú

2004”N
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‘ĺ’°‹ŰƒQƒmƒ€DNA•ĄťŒn
uƒQƒmƒ~ƒNƒXEƒvƒƒeƒIƒ~ƒNƒX‚̐V“WŠJ[ś•¨î•ń‚̉đÍ‚Ɖž—p[viĄ’†’‰sŠÄCjƒGƒkEƒeƒB[EƒGƒXA57-64•Ĺ
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‘ĺ’°‹ŰőF‘Ě•Ąť‚ĚŠJŽn‚Ć‚ť‚̐§Œä‚ÉŠÖ‚í‚éAAA+ƒX[ƒp[ƒtƒ@ƒ~ƒŠ[ƒ^ƒ“ƒpƒNŽż
ś‰ťŠw, 76ŠŞi11†j, 1440-1443•Ĺ
Œ´’˜˜_•ś
Su'etsugu, M., Takata, M., Kubota, T., Matsuda, Y. and Katayama, T. (2004)
Molecular mechanism of DNA replication-coupled inactivation of the initiator protein in Escherichia coli: Interaction of DnaA with the sliding clamp-loaded DNA and the sliding clamp-Hda complex
Genes Cells 9 (6), 509-522

Fujimitsu, K. and Katayama, T. (2004)
Reactivation of DnaA by DNA sequence-specific nucleotide exchange in vitro
Biochem. Biophys. Res. Commun. 322(2), 411-419

Ishida, T., Akimitsu, N., Kashioka, T., Hatano, M. (equal contributors), Kubota, T., Ogata, Y., Sekimizu, K., and Katayama, T. (2004)
DiaA, a novel DnaA-binding protein, ensures the initiation timing of E. coli chromosome replication
J. Biol. Chem. 279(44), 45546-45555

Shimuta, T., Nakano, K. (equal contributors), Yamaguchi, Y., Ozaki, S., Fujimitsu, K., Matsunaga, C., Noguchi, K., Emoto, A., and Katayama, T. (2004)
Novel heat-shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli
Genes Cells 9, 1151-1166

Žĺ—vŠw‰ď”­•\
Katayama, T.
DNA replication-dependent feedback against DnaA initiator activity
Keystone Symposia on Molecular and Cellular Biology "Bacterial Chromosomes", 2004”N2ŒŽ7`14“ú@•Ä‘ New MexicoB Santa Feiľ‘ҍu‰‰j

Katayama, T.
DnaA protein in Escherichia coli: Regulation and functional structure for initiation of chromosomal DNA replication.
The 1st Asian Symposium for Pharmaceutical Sciences, Fukuoka, Japan, January 30-31, 2004, pp72-77@(Oral presentation)

“ĄŒő˜a”VA•ĐŽR@•×
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2003”N
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×‹ŰőF‘Ě‚Ě•Ąť§Œä‹@\
–ňŠwŒ¤‹†‚̐i•ŕ, 19ŠŞ, 19-28•Ĺi–ňŠwŒ¤‹†§—ăŕ’cj
Œ´’˜˜_•ś

Su'etsugu, M., Emoto, A., Fujimitsu, K., Keyamura, K., and Katayama, T. (2003)
Transcriptional control for initiation of chromosomal replication in Escherichia coli: fluctuation of the level of origin transcription ensures timely initiation
Genes Cells 8 (9), 731-745.

Fujikawa, N., Kurumizaka, H., Nureki, O. (equal contributors), Terada, T., Shirouzu, M., Katayama, T., and Yokoyama, S. (2003)
Structural basis of replication origin recongnition by the DnaA protein
Nucleic Acids Res. 31(8), 2077-2086 .

Yoshida, Y., Obita, T., Kokusho, Y., Ohmura, T., Katayama, T., Ueda, T., and Imoto, T. (2003)
Identification of the region of Escherichia coli DnaA protein required for specific recognition of the DnaA box
Cell. Mol. Life Sci. 60(9), 1998-2008.

Higuchi, K., Katayama, T., Iwai, S., Hidaka, M., Horiuchi, T., and Maki, H. (2003)
Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro
Genes Cells 8 (5), 437-449.
F1000Prime„‘E˜_•ś

Žĺ—vŠw‰ď”­•\
Katayama, T., Su'etsugu, M., Kawakami, H., Shimuta, T., Suzuki, S., Ishida, T., Wakatsuki, T., and Fujimitsu, K.
Regulatory inactivation of the E. coli DnaA initiator: Molecular mechanisms in interactions of DnaA, Hda, and the replicase sliding clamp
EMBO Workshop On Replicon Theory, Villefranche-sur-mer (France), Jan 18-22, 2003 (Œű“Ş”­•\)

Tsutomu Katayama, Masayuki Su'etsugu, Toh-ru Shimuta, Hironori Kawakami, Shige-o Suzuki, Takuma Ishida, Kenji Keyamura, and Kazuyuki Fujimitsu,
Regulatory Inactivation of The Initiator Protein in E. coli: Roles of The AAA+ Motifs of DnaA and Hda Proteins,
5th International Conference on AAA Proteins, Warrenton, VA (USA), June 15-19, 2003, (p.A-19), Oral session

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“ú–{ˆâ“`Šw‰ď‘ć75‰ń‘ĺ‰ďAĺ‘äA2003”N9ŒŽ24“ú`26“úA(p.23)Aƒ[ƒNƒVƒ‡ƒbƒv

ěăLéA––ŽŸłKA•ĐŽR@•×A
DnaA‚̐§Œä“I•sŠˆŤ‰ť(RIDA)F\ŹˆöŽqHdaEpol IIIƒNƒ‰ƒ“ƒv•Ą‡‘̂̐¸ť‚Č‚ç‚тɐŤó‰đÍA
“ú–{ˆâ“`Šw‰ď‘ć75‰ń‘ĺ‰ďAĺ‘äA2003”N9ŒŽ24“ú`26“úA(p.103)Aˆę”ʍu‰‰iBest PaperÜj

Tsutomu Katayama, Masayuki Su'etsugu, Kazuyuki Fujimitsu, Hironori Kawakami, Toh-ru Shimuta, Kenji Keyamura, Takuma Ishida,
Regulatory elements for oriC and DnaA protein in initiation of chromosomal replication,
International Workshop for Escherichia coli Towards New Biology in the 21st Century, Awaji (Japan), Oct. 15-17, 2003, (p. 46), Oral presentation

Tsutomu Katayama, Masayuki Su'etsugu, Hironori Kawakami, Kenji Keyamura, Toh-ru Shimuta, Takuma Ishida and Kazuyuki Fujimitsu,
Replication cycle-coordinated regulations for DnaA initiator and oriC replicator in Escherichia coli,
The 4th International symposium on DNA Replication, Recombination and Repair, Awaji (Japan), Nov. 9-13, 2003, (p.32), Oral session

Tsutomu Katayama, Masayuki Su'etsugu, Hironori Kawakami, Kazuyuki Fujimitsu, Kenji Keyamura, Takuma Ishida, Toh-ru Shimuta,
Multiple regulations for the initiator and the replicator in E. coli chromosome
‘ć26‰ń“ú–{•ŞŽqś•¨Šw‰ď”N‰ďA2003”N12ŒŽ10“ú`13“úA(p.22)AƒVƒ“ƒ|ƒWƒEƒ€

2002”N
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×–EŽüŠú‚É‚¨‚Ż‚éDNA•Ąť‚̐§ŒäFŒ´Šjś•¨‚É‚¨‚Ż‚é•Ąť§Œä
uƒQƒmƒ€‚Ě•Ąť‚Ć•Ş”zviź‰eş•vEłˆä‹v—Y•ŇjƒVƒ…ƒvƒŠƒ“ƒK[ƒtƒFƒAƒ‰[ƒN“Œ‹ž
Œ´’˜˜_•ś
Nishida, S., Fujimitsu, K., Sekimizu, K., Ohmura, T., Ueda, T., and Katayama, T. (2002)
A nucleotide switch in E. coli DnaA protein initiates chromosomal replication: Evidence from a mutant DnaA protein defective in regulatory ATP hydrolysis in vitro and in vivo
J. Biol. Chem. 277 (17), 14986-14995.

Onogi, T., Ohsumi, K., Katayama, T., and Hiraga, S. (2002)
Replication-dependent recruitment of the beta-subunit of DNA polymerase III from cytsolic spaces to replication forks in Escherichia coli
J. Bacteriol. 184 (3), 867-870.

Obita, T., Iwura, T., Su'etsugu, M., Yoshida, Y., Tanaka, Y., Katayama, T., Ueda, T., and Imoto, T. (2002)
Determination of the secondary structure in solution of the Escherichia coli DnaA DNA-binding domain
Biochem. Biophys. Res. Commun. 299 (1), 42-48

Žĺ—vŠw‰ď”­•\
Katayama, T., Su'etsugu, S., Fujimitsu, K., Kawakami, H., and Kato, J.
The sliding clamp-dependent feedback regulation of DnaA function in the E. coli chromosomal replication cycle,
Keystone Symposia on Molecular and Cellular Biology "DNA Replication and Recombination", 2002”N1ŒŽ7`14“ú@•Ä‘ƒ†ƒ^BƒXƒm[ƒo[ƒhiŒű“Ş+ƒ|ƒXƒ^[”­•\j
(ŽQlj [Meeting Review] Replication, Recombination and Repair: Going for the Gold,
Molecular Cell (2002) 9, 471-480

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2001”N
‘ŕ
Katayama, T. (2001)
Feedback controls restrain the initiation of Escherichia coli chromosomal replication.
Mol. Microbiol. 41(1), 9-18.
Œ´’˜˜_•ś
Kato, J. and Katayama, T. (2001)
Hda, a novel DnaA-related protein, regulates the replication cycle in Escherichia coli.
EMBO J. 20 (15), 4253-4262.
F1000Prime„‘E˜_•ś

Su'etsugu, M., Kawakami, H. (equal contributors), Kurokawa, K., Kubota, T., Takata, M., and Katayama, T. (2001)
DNA replication-coupled inactivation of DnaA protein in vitro: a role for DnaA arginine-334 of the AAA+ Box VIII motif in ATP hydrolysis.
Mol. Microbiol. 40 (2), 376-386.

Katayama, T., Fujimitsu, K., and Ogawa, T. (2001)
Multiple pathways regulating DnaA function in Escherichia coli: Distinct roles for DnaA titration by the datA locus and the regulatory inactivation of DnaA.
Biochimie 83 (1), 13-17 (An invited paper for a special volume)

Kawakami, H., Iwura, T., Takata, M., Sekimizu, K., Hiraga, S., and Katayama, T. (2001)
Arrest of cell division and nucleoid partition by genetic alterations in the sliding clamp of the replicase and DnaA protein.
Mol. Gen. Genomics 266, 167-179.

Kubota, T., Ito, Y., Sekimizu, K., Tagaya, M., and Katayama, T. (2001)
DnaA protein Lys-415 is close to the ATP-binding site: ATP-pyridoxal affinity labeling
Biochem. Biophys. Res. Commun. 288 (5), 1141-1148 .

Žĺ—vŠw‰ď”­•\
Tsutomu Katayama, Makoto Takata, Hironori Kawakami, Masayuki Su'etsugu, Kazuyuki Fujimitsu, and Jun-ichi Kato,
Regulation of the replication initiator activity in E. coli: molecular mechanisms in accelerated hydrolysis of DnaA-bound ATP,
The Fourth International Meeting on AAA Proteins: Cellular Functions of AAA Proteins in Search of Common Molecular Basis, March 13-16, Kyoto , Japani2001jiŒű“Ş”­•\j

Tsutomu Katayama, Hironori Kawakami, Masayuki Su'etsugu, Kazuyuki Fujimitsu, Satoshi Nishida, Makoto Takata, and Jun-ichi Kato,
Regulatory inactivation of the DnaA initiation in Escherichia coli: the sliding clamp-dependent hydrolysis of DnaA-bound ATP,
The 3rd Fujihara International Seminar "Bacterial Cell Cycle 2001", Sept. 18-20, Osaka, Japan (2001)iŒű“Ş”­•\j

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‘ć24‰ń“ú–{•ŞŽqś•¨Šw‰ďƒ[ƒNƒVƒ‡ƒbƒvA‰Ą•lA12ŒŽ

2000”N
Œ´’˜˜_•ś
Takata, M., Guo, L., Katayama, T., Hase, M., Seyama, Y., Miki, T., and Sekimizu, K. (2000)
Mutant DnaA proteins defective in opening of oriC, the origin of chromosomal DNA replication in Escherichia coli.
Mol. Microbiol. 35 (2), 454-462
Žĺ—vŠw‰ď”­•\
Makoto Takata, Hironori Kawakami, Masayuki, Su'etsugu, Kazuyuki Fujimitsu, Tohru Ogawa, and Tsutomu Katayama,
Regulatory inactivation of DnaA protein; role and molecular mechanisms in accelerated hydrolysis of DnaA-bound ATP,
EMBO Workshop on "Cell Cycle and Nucleoid Organization in Bacteria" (2000”N9ŒŽ2-6“ú Texel, The Netherlands) Abstract p S-27iŒű“Ş”­•\j

•ĐŽR@•×A‚“c@˝A––ŽŸłKA“ĄŒő˜a”VAěăLéA‰Á“Ąˆę,
‚P‰ńŤ•Ąť‚É‚¨‚Ż‚éDnaA‚̐§Œä“I•sŠˆŤ‰ť‚Ě–đŠ„‚Ć•ŞŽq‹@\,
‘ć23‰ń“ú–{•ŞŽqś•¨Šw‰ďƒ[ƒNƒVƒ‡ƒbƒvu”÷ś•¨×–E•Ş—ô‚É‚¨‚Ż‚éőF‘Ěintegrity•ŰŽ‹@\, (2000”N12ŒŽ13-16“ú _ŒË‘Ű“WŽŚęA_ŒË‘Ű‰ď‹cęA_ŒËƒ|[ƒgƒsƒAƒzƒeƒ‹j

1999”N
‘ŕ
Tsutomu Katayama and Kazuhisa Sekimizu,
Inactivation of Escherichia coli DnaA protein by DNA polymerase III, and negative regulations for initiation of chromosomal replication,
Biochimie 81 (8), 835-840 (1999) (An invited review for a special issue).

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DNAƒ|ƒŠƒƒ‰[ƒ[‚̐V‹@”\FőF‘Ě•ĄťŠJŽn‚Ě•‰‚̐§Œä,
’`”’ŽżŠjŽ_y‘f, 44ŠŞA‚V†A845-853•Ĺi‚UŒŽ†ji1999j

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őF‘ĚDNA•Ąť‚̐§Œä,
‹ăB‘ĺŠwŒ¤‹†Đ‰î, 16ŠŞA33-34•Ĺi1999j

Œ´’˜˜_•ś
Kenji Kurokawa, Satoshi Nishida, Akiko Emoto, Kazuhisa Sekimizu, and Tsutomu Katayama,
Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coli,
EMBO J. 18 (23), 6642-6652 (1999).

Lei Guo, Tsutomu Katayama, Yousuke Seyama, Kazuhisa Sekimizu, and Takeyoshi Miki ,
Isolation and characterization of novel cold-sensitive dnaA mutants of Escherichia coli,
FEMS Microbiol. Lett. 176, 357-366 (1999).

Žĺ—vŠw‰ď”­•\
Tsutomu Katayama, Toshio Kubota, Kenji Kurokawa, Satoshi Nishida, Makoto Takata,, Akiko Emoto, Hironoti Kawakami, and Kazuhisa Sekimizu,
Regulatory inactivation of DnaA protein depends on loading of Pol III in vitro, and is coupled with DNA replication in vivo,
Workshop on the Bacterial Cell Cycle 1999, Abondance, France, March 1999. Abstract p14.iŒű“Ş”­•\j

Tsutomu Katayama,
Regulation of the replication cycle of the Escherichia coli chromosome,
The 1st International Genecell Workshop, Keihanna Science City, August 1999. Abstract p33.iŒű“Ş”­•\j

•ĐŽR@•×,
‘ĺ’°‹Ű‚̐őF‘Ě•Ąť‚đ§Œä‚ˇ‚é‹@\Œn‚Ć‚ť‚Ěˆâ“`Žq,
”÷ś•¨ƒQƒmƒ€ƒ[ƒNƒVƒ‡ƒbƒv (–źŒĂ‰Ž, 1999”N11ŒŽ)@u‰‰—vŽ|W p18.

•ĐŽR@•×, ‚“c@˝, ŠÖ…˜a‹v, ‰Á“Ąˆę,
DnaA’`”’Žż‚̐§Œä“I•sŠˆŤ‰ťiRIDAj‚Ěin vitro Ä\Ź,
“ú–{•ŞŽqś•¨Šw‰ď‘ć22‰ď”N‰ďƒ[ƒNƒVƒ‡ƒbƒv i•Ÿ‰Ş, 1999”N12ŒŽj@u‰‰—vŽ|W p242.

Tsutomu Katayama, Kenji Kurokawa, Satoshi Nishida, Toshio Kubota, Makoto Takata, Akiko Emoto, Hironori Kawakami, and Kazuhisa Sekimizu,
The initiator function of E. coli DnaA protein is inactivated by DNA polymerase III that is acting for DNA synthesis in vivo,
Keystome symposia on Molecular and Cellular Biology, New Mexico, USA, February 1999. Abstract p71.

Toshio Kubota, Tsutomu Katayama, and Kazuhisa Sekimizu,
Mechanism of the negative regulation of DNA replication initiation by interaction of DnaA protein and replisome,
Workshop on the Bacterial Cell Cycle 1999, Abondance, France, March 1999. Abstract p16.

Makoto Takata, Tsutomu Katayama, and Kazuhisa Sekimizu,
CedA; a novel factor to neutralize division inhibition caused by chrosomoal overreplication,
Workshop on the Bacterial Cell Cycle 1999, Abondance, France, March 1999. Abstract p26.

Tsutomu Katayama, Makoto Takata, Mazakazu Hatano, Hironori Kawakami, Masayuki Suetsugu, Kazuyuki Fujimitsu and Kazuhisa Sekimizu,
Regulatory inactivation of DnaA protein (RIDA); Molecular mechanism and significance in control for the replication cycle,
‘ć‚Q‰ń‚R‚qƒVƒ“ƒ|ƒWƒEƒ€ (_ŒË, 1999”N10ŒŽ)@u‰‰—vŽ|Wp19.iŒű“Ş”­•\j

1998”N
Œ´’˜˜_•ś
T. Katayama, T. Kubota, K. Kurokawa, E. Crooke, K. Sekimizu,
The initiator function of DnaA protein is negatively regulated by the sliding clamp of the E. coli chromosomal replicase,
Cell 94 (1), 61-71 (1998)

K. Kurokawa, T. Mizushima, T. Kubota, T. Tsuchiya, T. Katayama, K. Sekimizu,
A stimulation factor for hydrolysis of ATP bound to DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli,
Biochem. Biophys. Res. Commun. 243 (1), 90-95 (1998)

T. Mizushima, T. Takaki, T. Kubota, T. Tsuchiya, T. Miki, T. Katayama, K. Sekimizu,
Site-directed mutational analysis for the ATP binding of DnaA protein: functions of two conserved amino acids (Lys-178 and Asp-235) located in the ATP-binding domain of DnaA protein in vitro and in vivo,
J. Biol. Chem. 273 (33), 20847-20851 (1998)

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•ĐŽR@•×, ŒE“c•q•v, •ěŒ’Ž™, ź“c@’q, ‚“c@˝, ŠÖ…˜a‹v,
•ĄťŠJŽnˆöŽq‚ĆDNAƒ|ƒŠƒƒ‰[ƒ[‚ĚƒNƒƒXƒg[ƒN‚É‚ć‚é‘ĺ’°‹ŰőF‘Ě‚Ě•ĄťŠJŽn‚̐§Œä‹@\,
“ú–{ś‰ťŠw‰ď‘ć71‰ń”N‰ďƒVƒ“ƒ|ƒWƒEƒ€i–źŒĂ‰Ž, 1998”N10ŒŽj, ś‰ťŠw, 70(8), p. 679 (1998)

•ĐŽR@•×,
őF‘ĚDNA•ĄťƒTƒCƒNƒ‹‚Ě•‰‚̐§Œä,
‘ć‚S‰ń•ś•”Č‰ČŠwŒ¤‹†”ď“Á’č—ĚˆćŒ¤‹†iAjŒöŠJƒVƒ“ƒ|ƒWƒEƒ€u•ŞŽq×–Eś•¨Šw‚̐V‚ľ‚˘—Ź‚ęvi“Œ‹ž, 1998”N11ŒŽj

•ĐŽR@•×, •ěŒ’Ž™, ź“c@’q, ŒE“c•q•v, ‚“c@˝, ]–{ťŽq, ŠÖ…˜a‹v,
•ĄťŠJŽnƒ^ƒ“ƒpƒNŽżDnaA‚ĚƒkƒNƒŒƒIƒ`ƒh•ĎŠˇƒTƒCƒNƒ‹,
“ú–{•ŞŽqś•¨Šw‰ď‘ć21‰ń”N‰ďƒ[ƒNƒVƒ‡ƒbƒvi‰Ą•l, 1998”N12ŒŽj, u‰‰—vŽ|W p.205.

ŒE“c•q•v, •ĐŽR@•×, ŠÖ…˜a‹v,
DNAƒ|ƒŠƒƒ‰[ƒ[EƒXƒ‰ƒCƒfƒBƒ“ƒOƒNƒ‰ƒ“ƒvŒ`Ź‚É‚ć‚é•ĄťŠJŽn’`”’ŽżDnaA‚Ě•sŠˆŤ‰ť‚Ě•ŞŽq‹@\,
“ú–{ś‰ťŠw‰ď‘ć71‰ń”N‰ďƒ[ƒNƒVƒ‡ƒbƒvi–źŒĂ‰Ž, 1998”N10ŒŽj, ś‰ťŠw, 70(8), p. 724 (1998)

T. Katayama, K. Kubota, K. Kurokawa, M.Takata, T. Mizushima, E. Crooke, K. Sekimizu,
Negative regulation of DnaA protein activity for the control of replicational initiation at oriC: identification and characterization of a novel modulator for initiation,
Keystone Symposia on Molecular and Cellular Biology "Bacterial Chromosomes" (Santa Fe, USA; Feb., 1998), Abstracts p38.

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